STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tagg_0495Iron (metal) dependent repressor, DtxR family; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR000485:IPR000835:IPR001367; KEGG: dal:Dalk_2732 iron (metal) dependent repressor, DtxR family; PFAM: iron dependent repressor; regulatory protein MarR; SMART: iron dependent repressor; SPTR: B8D4E9 Iron dependent repressor; PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain. (126 aa)    
Predicted Functional Partners:
Tagg_0496
COGs: COG3634 Alkyl hydroperoxide reductase large subunit; KEGG: sfu:Sfum_3874 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: B8D4F0 Glutaredoxin-like protein.
  
  
 0.858
Tagg_0051
NADH ubiquinone oxidoreductase 20 kDa subunit; COGs: COG3260 Ni Fe-hydrogenase III small subunit; InterPro IPR006137; KEGG: ppd:Ppro_2791 NADH ubiquinone oxidoreductase, 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: B8D5G8 NADH ubiquinone oxidoreductase, 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
    
   0.728
Tagg_0624
COGs: COG3260 Ni Fe-hydrogenase III small subunit; InterPro IPR006137:IPR006138; KEGG: ppd:Ppro_0593 NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: B8D3R4 NADH-quinone oxidoreductase, B subunit; TIGRFAM: NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, B subunit; Belongs to the complex I 20 kDa subunit family.
    
   0.728
Tagg_0232
ABC-3 protein; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: tdn:Suden_2063 hypothetical protein; PFAM: ABC-3 protein; SPTR: B8D3L6 ABC-type Mn2+/Zn2+ transport system, permease component; PFAM: ABC 3 transport family.
  
  
 0.692
Tagg_0233
COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; KEGG: ppr:PBPRB1208 putative adhesion protein; SPTR: B8D3L7 ABC transporter, substrate binding protein; PFAM: Periplasmic solute binding protein family.
  
  
 0.675
Tagg_0234
ABC transporter related protein; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: vvy:VV1037 zinc ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: B8D3L8 ABC transporter, ATP binding protein; PFAM: ABC transporter.
  
  
 0.659
Tagg_0022
Zinc/iron permease; COGs: COG0428 divalent heavy-metal cations transporter; InterPro IPR003689; KEGG: psb:Psyr_1862 zinc transporter ZIP; PFAM: zinc/iron permease; SPTR: Q8U2T4 Putative uncharacterized protein; PFAM: ZIP Zinc transporter.
  
  
 0.641
Tagg_0498
SPTR: A3DL00 ParB domain protein nuclease.
     
 0.501
Tagg_0497
Hypothetical protein; KEGG: structural maintenance of chromosomes protein (EC:1.12.98.1 1.3.1.74); K06675 structural maintenance of chromosome 4; SPTR: B8D4F1 Putative uncharacterized protein; PFAM: Transcriptional regulator.
       0.497
Tagg_1407
DNA-directed RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.483
Your Current Organism:
Thermosphaera aggregans
NCBI taxonomy Id: 633148
Other names: T. aggregans DSM 11486, Thermosphaera aggregans DSM 11486, Thermosphaera aggregans M11TL, Thermosphaera aggregans str. DSM 11486, Thermosphaera aggregans strain DSM 11486
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.