Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Tagg_0806Transcriptional regulator, TrmB; InterPro IPR002831:IPR010163; PFAM: transcriptional regulator TrmB; SPTR: B8D4S9 CRISPR locus-related DNA-binding protein; TIGRFAM: CRISPR locus-related DNA-binding protein; PFAM: Sugar-specific transcriptional regulator TrmB; TIGRFAM: CRISPR locus-related DNA-binding protein. (208 aa)    
Predicted Functional Partners:
Tagg_0805
Putative transcriptional regulator, AsnC family; InterPro IPR000485:IPR010163; SPTR: B8D4S4 CRISPR-associated HTH regulatory protein, Csa3 family; TIGRFAM: CRISPR locus-related DNA-binding protein; PFAM: IclR helix-turn-helix domain; TIGRFAM: CRISPR locus-related DNA-binding protein.
     
 0.766
Tagg_1238
Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR001757:IPR001756:IPR006121:IPR008250:IPR 005834:IPR018303:IPR017969:IPR000150:IPR006403:IPR006416; KEGG: oan:Oant_3240 heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: A3MU36 Heavy metal translocating P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; [...]
  
  
 0.529
Tagg_0802
InterPro IPR010153; PFAM: CRISPR-associated protein, MJ0382; SPTR: B8D4S1 CRISPR-associated protein Cas5; PFAM: CRISPR-associated protein (Cas_Cas5).
     
 0.471
Tagg_0799
CRISPR-associated HD domain protein; InterPro IPR006483; SPTR: B8D4R8 Putative uncharacterized protein; TIGRFAM: CRISPR-associated HD domain protein; TIGRFAM: CRISPR-associated HD domain protein.
     
 0.460
Tagg_0803
CRISPR-associated autoregulator, DevR family; COGs: COG1857 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR002764:IPR010154; PFAM: CRISPR-associated regulatory Csa2 family protein; SPTR: B8D4S2 CRISPR-associated autoregulator, DevR family; TIGRFAM: CRISPR-associated regulatory protein, Csa2 family; CRISPR-associated autoregulator DevR family; PFAM: CRISPR-associated negative autoregulator DevR/Csa2; TIGRFAM: CRISPR-associated autoregulator DevR family; CRISPR-associated regulatory protein, Csa2 family.
     
 0.460
Tagg_0804
Hypothetical protein; SPTR: B8D4S3 Putative uncharacterized protein.
     
 0.455
Tagg_0800
CRISPR-associated helicase Cas3; COGs: COG1203 helicase; InterPro IPR001650:IPR000408:IPR006474; KEGG: amc:MADE_00865 CRISPR-associated helicase Cas3; PFAM: helicase domain protein; SMART: helicase domain protein; SPTR: B8D4R9 CRISPR-associated ATP-dependent RNA helicase-like protein; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3.
       0.441
Your Current Organism:
Thermosphaera aggregans
NCBI taxonomy Id: 633148
Other names: T. aggregans DSM 11486, Thermosphaera aggregans DSM 11486, Thermosphaera aggregans M11TL, Thermosphaera aggregans str. DSM 11486, Thermosphaera aggregans strain DSM 11486
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