STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tagg_0907Archease family protein; COGs: COG1371 conserved hypothetical protein; InterPro IPR002804; KEGG: similar to CG6353 CG6353-PA; PFAM: protein of unknown function DUF101; SPTR: B8D5T4 DUF101 domain containing protein; PFAM: Archease protein family (DUF101/UPF0211). (155 aa)    
Predicted Functional Partners:
rtcB
Protein of unknown function UPF0027; COGs: COG1690 conserved hypothetical protein; InterPro IPR001233; KEGG: pca:Pcar_0019 hypothetical protein; PFAM: protein of unknown function UPF0027; SPTR: B8D605 Putative uncharacterized protein; PFAM: Uncharacterized protein family UPF0027; Belongs to the RtcB family.
 
 0.941
prf1
Peptide chain release factor subunit 1 (aeRF-1); Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
  
    0.670
rbcL
Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily.
       0.604
rtcA
RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
 
 
 
 0.587
Tagg_0138
Putative RNA methylase; COGs: COG1041 DNA modification methylase; InterPro IPR002296:IPR000241:IPR002052; KEGG: similar to CG1074-PA; PFAM: putative RNA methylase; SPTR: B8D434 Putative RNA methylase; PFAM: Putative RNA methylase family UPF0020; TIGRFAM: conserved hypothetical protein TIGR01177.
  
     0.421
Your Current Organism:
Thermosphaera aggregans
NCBI taxonomy Id: 633148
Other names: T. aggregans DSM 11486, Thermosphaera aggregans DSM 11486, Thermosphaera aggregans M11TL, Thermosphaera aggregans str. DSM 11486, Thermosphaera aggregans strain DSM 11486
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.