Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADL01318.1PFAM: Aldehyde Dehydrogenase; KEGG: oan:Oant_0271 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (505 aa)    
Predicted Functional Partners:
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.912
ADK99567.1
PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: pst:PSPTO_2182 oxidoreductase, zinc-binding.
  
 0.911
ADL00136.1
PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: mkm:Mkms_1883 alcohol dehydrogenase.
  
 0.911
ADL02434.1
KEGG: pzu:PHZ_c2025 alcohol dehydrogenase, class III; TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 0.911
ADL00058.1
PFAM: acetyl-CoA hydrolase/transferase; manually curated; KEGG: cak:Caul_5056 succinate CoA transferase; TIGRFAM: succinate CoA transferase.
  
 
 0.905
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
      0.877
ADL01317.1
PFAM: helix-turn-helix Fis-type; KEGG: mlo:mll6640 transcriptional regulator.
 
 
 
 0.818
ADL01295.1
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.578
ADK99924.1
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; Enoyl-CoA hydratase/isomerase; KEGG: ccs:CCNA_00074 multifunctional fatty acid oxidation complex subunit alpha FadJ.
  
 0.488
ADL02407.1
KEGG: ccs:CCNA_03722 glutamate synthase (NADPH) large chain; PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase; glutamate synthase alpha subunit domain protein; glutamine amidotransferase class-II.
  
  
 0.476
Your Current Organism:
Brevundimonas subvibrioides
NCBI taxonomy Id: 633149
Other names: B. subvibrioides ATCC 15264, Brevundimonas subvibrioides ATCC 15264, Brevundimonas subvibrioides CB81, Brevundimonas subvibrioides DSM 4735, Brevundimonas subvibrioides LMG 14903, Brevundimonas subvibrioides str. ATCC 15264, Brevundimonas subvibrioides strain ATCC 15264
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