node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SIS49831.1 | SIS53018.1 | SAMN05421759_10136 | SAMN05421759_101236 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA helicase RecQ. | 0.889 |
SIS49831.1 | SIS97551.1 | SAMN05421759_10136 | SAMN05421759_10886 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA helicase, Rep family. | 0.965 |
SIS49831.1 | SIS99317.1 | SAMN05421759_10136 | SAMN05421759_1098 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Relaxase/Mobilisation nuclease domain-containing protein. | 0.782 |
SIS49831.1 | polA | SAMN05421759_10136 | SAMN05421759_101301 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
SIS49831.1 | topA | SAMN05421759_10136 | SAMN05421759_108120 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.877 |
SIS52350.1 | SIS53018.1 | SAMN05421759_101199 | SAMN05421759_101236 | DNA helicase/exodeoxyribonuclease V, subunit A; Belongs to the helicase family. UvrD subfamily. | ATP-dependent DNA helicase RecQ. | 0.700 |
SIS52350.1 | SIS97551.1 | SAMN05421759_101199 | SAMN05421759_10886 | DNA helicase/exodeoxyribonuclease V, subunit A; Belongs to the helicase family. UvrD subfamily. | ATP-dependent DNA helicase, Rep family. | 0.709 |
SIS52350.1 | SIS99317.1 | SAMN05421759_101199 | SAMN05421759_1098 | DNA helicase/exodeoxyribonuclease V, subunit A; Belongs to the helicase family. UvrD subfamily. | Relaxase/Mobilisation nuclease domain-containing protein. | 0.935 |
SIS52350.1 | polA | SAMN05421759_101199 | SAMN05421759_101301 | DNA helicase/exodeoxyribonuclease V, subunit A; Belongs to the helicase family. UvrD subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.633 |
SIS53018.1 | SIS49831.1 | SAMN05421759_101236 | SAMN05421759_10136 | ATP-dependent DNA helicase RecQ. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.889 |
SIS53018.1 | SIS52350.1 | SAMN05421759_101236 | SAMN05421759_101199 | ATP-dependent DNA helicase RecQ. | DNA helicase/exodeoxyribonuclease V, subunit A; Belongs to the helicase family. UvrD subfamily. | 0.700 |
SIS53018.1 | SIS97551.1 | SAMN05421759_101236 | SAMN05421759_10886 | ATP-dependent DNA helicase RecQ. | ATP-dependent DNA helicase, Rep family. | 0.984 |
SIS53018.1 | SIS99317.1 | SAMN05421759_101236 | SAMN05421759_1098 | ATP-dependent DNA helicase RecQ. | Relaxase/Mobilisation nuclease domain-containing protein. | 0.501 |
SIS53018.1 | polA | SAMN05421759_101236 | SAMN05421759_101301 | ATP-dependent DNA helicase RecQ. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.995 |
SIS53018.1 | topA | SAMN05421759_101236 | SAMN05421759_108120 | ATP-dependent DNA helicase RecQ. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.994 |
SIS95208.1 | SIS99317.1 | SAMN05421759_107122 | SAMN05421759_1098 | Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily protein. | Relaxase/Mobilisation nuclease domain-containing protein. | 0.507 |
SIS97551.1 | SIS49831.1 | SAMN05421759_10886 | SAMN05421759_10136 | ATP-dependent DNA helicase, Rep family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.965 |
SIS97551.1 | SIS52350.1 | SAMN05421759_10886 | SAMN05421759_101199 | ATP-dependent DNA helicase, Rep family. | DNA helicase/exodeoxyribonuclease V, subunit A; Belongs to the helicase family. UvrD subfamily. | 0.709 |
SIS97551.1 | SIS53018.1 | SAMN05421759_10886 | SAMN05421759_101236 | ATP-dependent DNA helicase, Rep family. | ATP-dependent DNA helicase RecQ. | 0.984 |
SIS97551.1 | SIS99317.1 | SAMN05421759_10886 | SAMN05421759_1098 | ATP-dependent DNA helicase, Rep family. | Relaxase/Mobilisation nuclease domain-containing protein. | 0.477 |