node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SIS52100.1 | SIT10623.1 | SAMN05421759_101185 | SAMN05421759_11643 | Methyltransferase domain-containing protein. | Hypothetical protein; Belongs to the GcvT family. | 0.423 |
SIS64549.1 | SIS71061.1 | SAMN05421759_10229 | SAMN05421759_102540 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.988 |
SIS64549.1 | SIT10623.1 | SAMN05421759_10229 | SAMN05421759_11643 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Hypothetical protein; Belongs to the GcvT family. | 0.514 |
SIS71061.1 | SIS64549.1 | SAMN05421759_102540 | SAMN05421759_10229 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.988 |
SIS71061.1 | SIT10623.1 | SAMN05421759_102540 | SAMN05421759_11643 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Hypothetical protein; Belongs to the GcvT family. | 0.514 |
SIS71173.1 | SIS87887.1 | SAMN05421759_102550 | SAMN05421759_10550 | Iron-binding apoprotein IscA; Belongs to the HesB/IscA family. | Monothiol glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.885 |
SIS71173.1 | SIT10623.1 | SAMN05421759_102550 | SAMN05421759_11643 | Iron-binding apoprotein IscA; Belongs to the HesB/IscA family. | Hypothetical protein; Belongs to the GcvT family. | 0.615 |
SIS87800.1 | SIS87887.1 | SAMN05421759_10543 | SAMN05421759_10550 | Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family. | Monothiol glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.866 |
SIS87800.1 | SIT10623.1 | SAMN05421759_10543 | SAMN05421759_11643 | Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family. | Hypothetical protein; Belongs to the GcvT family. | 0.599 |
SIS87887.1 | SIS71173.1 | SAMN05421759_10550 | SAMN05421759_102550 | Monothiol glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | Iron-binding apoprotein IscA; Belongs to the HesB/IscA family. | 0.885 |
SIS87887.1 | SIS87800.1 | SAMN05421759_10550 | SAMN05421759_10543 | Monothiol glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family. | 0.866 |
SIS87887.1 | SIT10623.1 | SAMN05421759_10550 | SAMN05421759_11643 | Monothiol glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | Hypothetical protein; Belongs to the GcvT family. | 0.614 |
SIT10614.1 | SIT10623.1 | SAMN05421759_11642 | SAMN05421759_11643 | Fructosamine-3-kinase. | Hypothetical protein; Belongs to the GcvT family. | 0.811 |
SIT10614.1 | SIT10635.1 | SAMN05421759_11642 | SAMN05421759_11644 | Fructosamine-3-kinase. | ATP-binding cassette, subfamily B, MsbA. | 0.532 |
SIT10614.1 | SIT10646.1 | SAMN05421759_11642 | SAMN05421759_11645 | Fructosamine-3-kinase. | Protein tyrosine/serine phosphatase. | 0.571 |
SIT10623.1 | SIS52100.1 | SAMN05421759_11643 | SAMN05421759_101185 | Hypothetical protein; Belongs to the GcvT family. | Methyltransferase domain-containing protein. | 0.423 |
SIT10623.1 | SIS64549.1 | SAMN05421759_11643 | SAMN05421759_10229 | Hypothetical protein; Belongs to the GcvT family. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.514 |
SIT10623.1 | SIS71061.1 | SAMN05421759_11643 | SAMN05421759_102540 | Hypothetical protein; Belongs to the GcvT family. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.514 |
SIT10623.1 | SIS71173.1 | SAMN05421759_11643 | SAMN05421759_102550 | Hypothetical protein; Belongs to the GcvT family. | Iron-binding apoprotein IscA; Belongs to the HesB/IscA family. | 0.615 |
SIT10623.1 | SIS87800.1 | SAMN05421759_11643 | SAMN05421759_10543 | Hypothetical protein; Belongs to the GcvT family. | Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family. | 0.599 |