STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GTF2H3General transcription factor IIH subunit 3. (301 aa)    
Predicted Functional Partners:
Gtf2h2
General transcription factor IIH subunit.
   
 0.991
Mnat1
CDK-activating kinase assembly factor MAT1.
    
 0.988
CDK7
Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily.
   
 0.988
hay
DNA excision repair protein haywire.
    
 0.987
ERCC2
TFIIH basal transcription factor complex helicase XPD subunit.
    
 0.987
GTF2E1
General transcription factor IIE subunit 1.
   
 0.973
GTF2E2
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
    
 0.971
tbp-1
TATA-box-binding protein.
   
 0.955
TfIIFalpha
Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.
    
 0.952
Polr2b
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.939
Your Current Organism:
Trichinella spiralis
NCBI taxonomy Id: 6334
Other names: T. spiralis
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.