STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PABPC4Polyadenylate-binding protein 1. (906 aa)    
Predicted Functional Partners:
pan3
PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]
    
 0.955
inf-1
Eukaryotic initiation factor 4A; Belongs to the DEAD box helicase family.
 
 
 0.942
Atx2
Ataxin-2-like protein.
   
 
 0.928
Eif4g1
Eukaryotic translation initiation factor 4 gamma 1.
   
 0.905
EIF4G3
Eukaryotic translation initiation factor 4 gamma 3.
   
 0.905
PAIP1
Polyadenylate-binding protein-interacting protein 1.
   
 0.905
GSPT2
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B.
   
 0.902
Cbp80
Nuclear cap-binding protein subunit 1.
   
 0.869
ife-3
Eukaryotic translation initiation factor 4E-3; Belongs to the eukaryotic initiation factor 4E family.
   
 0.869
T01_4132
Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family.
   
 0.869
Your Current Organism:
Trichinella spiralis
NCBI taxonomy Id: 6334
Other names: T. spiralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.