hddc2 protein (Trichinella spiralis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

hddc2

HD domain-containing protein 2. (207 aa)

Predicted Functional Partners:

IMPDH1

0.697

Prkag2

0.675

DEADC1

0.635

guaD

0.635

punA

0.600

T01_9659

0.600

punA-2

0.600

Pgp

0.564

Gmps

0.461

Your Current Organism:

Trichinella spiralis

NCBI taxonomy Id: 6334
Other names: T. spiralis

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DEADC1	Gmps	A0A0V1BEN7	A0A0V1BPK4	tRNA-specific adenosine deaminase 2.	GMP synthase [glutamine-hydrolyzing].	0.486
DEADC1	IMPDH1	A0A0V1BEN7	A0A0V1BR35	tRNA-specific adenosine deaminase 2.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.470
DEADC1	T01_9659	A0A0V1BEN7	A0A0V1BJE4	tRNA-specific adenosine deaminase 2.	Putative purine nucleoside phosphorylase.	0.577
DEADC1	guaD	A0A0V1BEN7	E5SHT5	tRNA-specific adenosine deaminase 2.	Guanine deaminase.	0.439
DEADC1	hddc2	A0A0V1BEN7	E5SNQ8	tRNA-specific adenosine deaminase 2.	HD domain-containing protein 2.	0.635
DEADC1	punA	A0A0V1BEN7	A0A0V1B022	tRNA-specific adenosine deaminase 2.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.577
DEADC1	punA-2	A0A0V1BEN7	E5S545	tRNA-specific adenosine deaminase 2.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.577
Gmps	DEADC1	A0A0V1BPK4	A0A0V1BEN7	GMP synthase [glutamine-hydrolyzing].	tRNA-specific adenosine deaminase 2.	0.486
Gmps	IMPDH1	A0A0V1BPK4	A0A0V1BR35	GMP synthase [glutamine-hydrolyzing].	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.997
Gmps	Prkag2	A0A0V1BPK4	A0A0V1ASV9	GMP synthase [glutamine-hydrolyzing].	5'-AMP-activated protein kinase subunit gamma-2.	0.916
Gmps	T01_9659	A0A0V1BPK4	A0A0V1BJE4	GMP synthase [glutamine-hydrolyzing].	Putative purine nucleoside phosphorylase.	0.466
Gmps	guaD	A0A0V1BPK4	E5SHT5	GMP synthase [glutamine-hydrolyzing].	Guanine deaminase.	0.460
Gmps	hddc2	A0A0V1BPK4	E5SNQ8	GMP synthase [glutamine-hydrolyzing].	HD domain-containing protein 2.	0.461
Gmps	punA	A0A0V1BPK4	A0A0V1B022	GMP synthase [glutamine-hydrolyzing].	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.466
Gmps	punA-2	A0A0V1BPK4	E5S545	GMP synthase [glutamine-hydrolyzing].	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.466
IMPDH1	DEADC1	A0A0V1BR35	A0A0V1BEN7	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	tRNA-specific adenosine deaminase 2.	0.470
IMPDH1	Gmps	A0A0V1BR35	A0A0V1BPK4	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	GMP synthase [glutamine-hydrolyzing].	0.997
IMPDH1	Prkag2	A0A0V1BR35	A0A0V1ASV9	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	5'-AMP-activated protein kinase subunit gamma-2.	0.639
IMPDH1	T01_9659	A0A0V1BR35	A0A0V1BJE4	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Putative purine nucleoside phosphorylase.	0.719
IMPDH1	guaD	A0A0V1BR35	E5SHT5	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Guanine deaminase.	0.470