STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MLH1DNA mismatch repair protein Mlh1. (714 aa)    
Predicted Functional Partners:
Mnx1
DNA mismatch repair protein Msh2.
 
 0.992
Msh6
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.986
MLH3
DNA mismatch repair protein Mlh3.
    
 0.984
Brip1-2
Fanconi anemia group J-like protein.
   
 0.961
MSH5
MutS-like protein 5.
 
 0.927
MSH4
MutS-like protein 4.
 
 0.923
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.890
INO80
DNA helicase INO80.
  
 0.871
him-6
Bloom syndrome-like protein.
  
 0.871
fen1
Flap endonuclease 1.
   
 0.863
Your Current Organism:
Trichinella spiralis
NCBI taxonomy Id: 6334
Other names: T. spiralis
Server load: low (22%) [HD]