STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lig1DNA ligase. (807 aa)    
Predicted Functional Partners:
XRCC1
DNA repair protein XRCC1.
   
 0.999
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.999
Xrcc5
X-ray repair cross-complementing protein 5.
   
 0.986
Rfc4
Replication factor C subunit 4.
   
 0.960
T4E_5521
DNA polymerase delta catalytic subunit.
   
 0.959
ercc5
DNA repair protein-like protein.
  
 0.956
Pole
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
   
 0.929
Mrpl30
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
  
 0.926
mcm5-a
DNA helicase; Belongs to the MCM family.
   
  
 0.919
Rfc1
Replication factor C subunit 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
 0.898
Your Current Organism:
Trichinella pseudospiralis
NCBI taxonomy Id: 6337
Other names: T. pseudospiralis
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