STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHK28187.1Uncharacterized protein; Manually curated. (168 aa)    
Predicted Functional Partners:
rpmF
LSU ribosomal protein L32P; Belongs to the bacterial ribosomal protein bL32 family.
  
  
 0.981
rpsC
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
   0.967
rplK
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
   
    0.916
rplA
LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
   
    0.888
rpsP
SSU ribosomal protein S16P; Belongs to the bacterial ribosomal protein bS16 family.
  
    0.871
rpsF
SSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA.
  
    0.871
rpsB
SSU ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family.
  
    0.868
infC
Bacterial translation initiation factor 3 (bIF-3); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
  
    0.867
rplU
Large subunit ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
    0.858
trmD
tRNA (Guanine37-N(1)-) methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
  
    0.855
Your Current Organism:
Rhodothermus profundi
NCBI taxonomy Id: 633813
Other names: DSM 22212, JCM 15944, R. profundi, Rhodothermus profundi Marteinsson et al. 2010, Rhodothermus sp. PRI 2902, strain PRI 2902
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