node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHK12773.1 | SHK14719.1 | SAMN04488087_0378 | SAMN04488087_0446 | 2-oxoisovalerate dehydrogenase E1 component. | 2-oxoisovalerate dehydrogenase E1 component. | 0.999 |
SHK12773.1 | SHK36712.1 | SAMN04488087_0378 | SAMN04488087_0984 | 2-oxoisovalerate dehydrogenase E1 component. | 2-oxoglutarate dehydrogenase E2 component. | 0.999 |
SHK12773.1 | SHK48146.1 | SAMN04488087_0378 | SAMN04488087_1226 | 2-oxoisovalerate dehydrogenase E1 component. | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.933 |
SHK12773.1 | SHK56329.1 | SAMN04488087_0378 | SAMN04488087_1396 | 2-oxoisovalerate dehydrogenase E1 component. | 2-oxoglutarate dehydrogenase E1 component. | 0.999 |
SHK12773.1 | SHK96825.1 | SAMN04488087_0378 | SAMN04488087_2419 | 2-oxoisovalerate dehydrogenase E1 component. | Dihydrolipoamide dehydrogenase. | 0.999 |
SHK12773.1 | SHL06566.1 | SAMN04488087_0378 | SAMN04488087_2639 | 2-oxoisovalerate dehydrogenase E1 component. | 2-oxoisovalerate dehydrogenase E1 component. | 0.999 |
SHK12773.1 | merA | SAMN04488087_0378 | SAMN04488087_1217 | 2-oxoisovalerate dehydrogenase E1 component. | Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.999 |
SHK12773.1 | pdhA | SAMN04488087_0378 | SAMN04488087_1227 | 2-oxoisovalerate dehydrogenase E1 component. | Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.941 |
SHK12773.1 | sucC | SAMN04488087_0378 | SAMN04488087_1957 | 2-oxoisovalerate dehydrogenase E1 component. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.703 |
SHK12773.1 | sucD | SAMN04488087_0378 | SAMN04488087_1789 | 2-oxoisovalerate dehydrogenase E1 component. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.546 |
SHK14719.1 | SHK12773.1 | SAMN04488087_0446 | SAMN04488087_0378 | 2-oxoisovalerate dehydrogenase E1 component. | 2-oxoisovalerate dehydrogenase E1 component. | 0.999 |
SHK14719.1 | SHK36712.1 | SAMN04488087_0446 | SAMN04488087_0984 | 2-oxoisovalerate dehydrogenase E1 component. | 2-oxoglutarate dehydrogenase E2 component. | 0.999 |
SHK14719.1 | SHK48146.1 | SAMN04488087_0446 | SAMN04488087_1226 | 2-oxoisovalerate dehydrogenase E1 component. | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.936 |
SHK14719.1 | SHK56329.1 | SAMN04488087_0446 | SAMN04488087_1396 | 2-oxoisovalerate dehydrogenase E1 component. | 2-oxoglutarate dehydrogenase E1 component. | 0.999 |
SHK14719.1 | SHK96825.1 | SAMN04488087_0446 | SAMN04488087_2419 | 2-oxoisovalerate dehydrogenase E1 component. | Dihydrolipoamide dehydrogenase. | 0.999 |
SHK14719.1 | SHL06566.1 | SAMN04488087_0446 | SAMN04488087_2639 | 2-oxoisovalerate dehydrogenase E1 component. | 2-oxoisovalerate dehydrogenase E1 component. | 0.999 |
SHK14719.1 | merA | SAMN04488087_0446 | SAMN04488087_1217 | 2-oxoisovalerate dehydrogenase E1 component. | Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.999 |
SHK14719.1 | pdhA | SAMN04488087_0446 | SAMN04488087_1227 | 2-oxoisovalerate dehydrogenase E1 component. | Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.948 |
SHK14719.1 | sucC | SAMN04488087_0446 | SAMN04488087_1957 | 2-oxoisovalerate dehydrogenase E1 component. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.703 |
SHK14719.1 | sucD | SAMN04488087_0446 | SAMN04488087_1789 | 2-oxoisovalerate dehydrogenase E1 component. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.546 |