node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aspC | purA | AUT07_00561 | AUT07_00607 | Aspartate aminotransferase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.912 |
aspC | pyrB | AUT07_00561 | AUT07_00634 | Aspartate aminotransferase. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.900 |
aspC | pyrI | AUT07_00561 | AUT07_00633 | Aspartate aminotransferase. | Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.900 |
carA | carB | AUT07_00261 | AUT07_00260 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Carbamoyl-phosphate synthase large chain. | 0.999 |
carA | fre | AUT07_00261 | AUT07_00510 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | NAD(P)H-flavin reductase. | 0.822 |
carA | pyrB | AUT07_00261 | AUT07_00634 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.998 |
carA | pyrC | AUT07_00261 | AUT07_00502 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.529 |
carA | pyrD | AUT07_00261 | AUT07_00557 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.852 |
carA | pyrE | AUT07_00261 | AUT07_00121 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.822 |
carA | pyrF | AUT07_00261 | AUT07_00052 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.824 |
carA | pyrI | AUT07_00261 | AUT07_00633 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.951 |
carB | carA | AUT07_00260 | AUT07_00261 | Carbamoyl-phosphate synthase large chain. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.999 |
carB | fre | AUT07_00260 | AUT07_00510 | Carbamoyl-phosphate synthase large chain. | NAD(P)H-flavin reductase. | 0.840 |
carB | purA | AUT07_00260 | AUT07_00607 | Carbamoyl-phosphate synthase large chain. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.525 |
carB | pyrB | AUT07_00260 | AUT07_00634 | Carbamoyl-phosphate synthase large chain. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.998 |
carB | pyrC | AUT07_00260 | AUT07_00502 | Carbamoyl-phosphate synthase large chain. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.575 |
carB | pyrD | AUT07_00260 | AUT07_00557 | Carbamoyl-phosphate synthase large chain. | Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.863 |
carB | pyrE | AUT07_00260 | AUT07_00121 | Carbamoyl-phosphate synthase large chain. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.868 |
carB | pyrF | AUT07_00260 | AUT07_00052 | Carbamoyl-phosphate synthase large chain. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.856 |
carB | pyrI | AUT07_00260 | AUT07_00633 | Carbamoyl-phosphate synthase large chain. | Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.956 |