STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFP60882.1Acyl dehydratase. (150 aa)    
Predicted Functional Partners:
SFP69907.1
Citrate lyase subunit beta / citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family.
 
 
 0.923
SFP89117.1
Serine protease Do; Belongs to the peptidase S1C family.
    
  0.815
SFP61281.1
3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.778
SFP68182.1
Citrate lyase subunit beta / citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family.
 
 
 0.772
SFP54038.1
3-methylcrotonyl-CoA carboxylase beta subunit.
 
 
 0.746
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 
  0.700
sucD
succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 
  0.682
SFP54052.1
isovaleryl-CoA dehydrogenase.
  
  0.679
SFP54006.1
3-methylcrotonyl-CoA carboxylase alpha subunit.
    
  0.606
SFP60904.1
cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases.
    
  0.581
Your Current Organism:
Sphingomonas rubra
NCBI taxonomy Id: 634430
Other names: CGMCC 1.9113, JCM 16230, S. rubra, Sphingomonas rubra Huo et al. 2011, Sphingomonas sp. BH3, strain BH3
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