node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHF78846.1 | SHF78874.1 | SAMN05216361_0404 | SAMN05216361_0405 | tRNA (mo5U34)-methyltransferase. | Hypothetical protein. | 0.416 |
SHF78846.1 | SHF91585.1 | SAMN05216361_0404 | SAMN05216361_0867 | tRNA (mo5U34)-methyltransferase. | Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family. | 0.455 |
SHF78846.1 | SHH11415.1 | SAMN05216361_0404 | SAMN05216361_3826 | tRNA (mo5U34)-methyltransferase. | TIGR03503 family protein. | 0.441 |
SHF78846.1 | SHH23781.1 | SAMN05216361_0404 | SAMN05216361_4123 | tRNA (mo5U34)-methyltransferase. | Protein of unknown function. | 0.442 |
SHF78846.1 | SHH23810.1 | SAMN05216361_0404 | SAMN05216361_4124 | tRNA (mo5U34)-methyltransferase. | Ca-activated chloride channel family protein. | 0.507 |
SHF78846.1 | gcvP | SAMN05216361_0404 | SAMN05216361_1312 | tRNA (mo5U34)-methyltransferase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.686 |
SHF78846.1 | glyA | SAMN05216361_0404 | SAMN05216361_2503 | tRNA (mo5U34)-methyltransferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.569 |
SHF78846.1 | mnmC | SAMN05216361_0404 | SAMN05216361_2165 | tRNA (mo5U34)-methyltransferase. | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.484 |
SHF78846.1 | trpS | SAMN05216361_0404 | SAMN05216361_3353 | tRNA (mo5U34)-methyltransferase. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.408 |
SHF78846.1 | ubiB | SAMN05216361_0404 | SAMN05216361_1694 | tRNA (mo5U34)-methyltransferase. | Ubiquinone biosynthesis protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | 0.455 |
SHF78874.1 | SHF78846.1 | SAMN05216361_0405 | SAMN05216361_0404 | Hypothetical protein. | tRNA (mo5U34)-methyltransferase. | 0.416 |
SHF91585.1 | SHF78846.1 | SAMN05216361_0867 | SAMN05216361_0404 | Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family. | tRNA (mo5U34)-methyltransferase. | 0.455 |
SHH11415.1 | SHF78846.1 | SAMN05216361_3826 | SAMN05216361_0404 | TIGR03503 family protein. | tRNA (mo5U34)-methyltransferase. | 0.441 |
SHH23781.1 | SHF78846.1 | SAMN05216361_4123 | SAMN05216361_0404 | Protein of unknown function. | tRNA (mo5U34)-methyltransferase. | 0.442 |
SHH23781.1 | SHH23810.1 | SAMN05216361_4123 | SAMN05216361_4124 | Protein of unknown function. | Ca-activated chloride channel family protein. | 0.951 |
SHH23810.1 | SHF78846.1 | SAMN05216361_4124 | SAMN05216361_0404 | Ca-activated chloride channel family protein. | tRNA (mo5U34)-methyltransferase. | 0.507 |
SHH23810.1 | SHH23781.1 | SAMN05216361_4124 | SAMN05216361_4123 | Ca-activated chloride channel family protein. | Protein of unknown function. | 0.951 |
gcvP | SHF78846.1 | SAMN05216361_1312 | SAMN05216361_0404 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | tRNA (mo5U34)-methyltransferase. | 0.686 |
gcvP | glyA | SAMN05216361_1312 | SAMN05216361_2503 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.997 |
gcvP | mnmC | SAMN05216361_1312 | SAMN05216361_2165 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.690 |