STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHF82830.1RNA polymerase sigma-70 factor, ECF subfamily. (173 aa)    
Predicted Functional Partners:
SHF82804.1
Hypothetical protein.
 
 
 0.978
SHF82776.1
Hypothetical protein.
 
     0.862
SHF74146.1
RNA polymerase sigma-70 factor, ECF subfamily.
  
     0.763
SHG59966.1
sigma-E factor negative regulatory protein RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplas [...]
  
 
 0.746
SHG44576.1
RNA polymerase sigma-70 factor, ECF subfamily.
  
   
 0.740
SHF82856.1
Subtilase family protein.
 
     0.720
SHG76452.1
RNA polymerase sigma-70 factor, ECF subfamily.
  
   
 0.643
SHG73835.1
RNA polymerase sigma-70 factor, ECF subfamily.
  
   
 0.642
SHG76489.1
Anti-sigma-K factor RskA.
 
 
 
 0.607
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.597
Your Current Organism:
Marisediminitalea aggregata
NCBI taxonomy Id: 634436
Other names: Aestuariibacter aggregatus, Aestuariibacter aggregatus Wang et al. 2010, Alteromonas sp. WH169, CGMCC 1.8995, LMG 25283, LMG:25283, M. aggregata, Marisediminitalea aggregata (Wang et al. 2010) Zhang et al., strain WH169
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