STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHG11715.1Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (890 aa)    
Predicted Functional Partners:
SHG11681.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.999
SHG11648.1
Dihydrolipoamide dehydrogenase.
 
 
 0.986
SHH03564.1
2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase).
 
 0.964
SHG32406.1
2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.949
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.877
SHG03872.1
Oxaloacetate decarboxylase, alpha subunit.
    
 0.875
SHG35222.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.860
SHG21980.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
    
 0.843
SHG93463.1
Malate dehydrogenase (oxaloacetate-decarboxylating).
    
 0.843
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
     
 0.841
Your Current Organism:
Marisediminitalea aggregata
NCBI taxonomy Id: 634436
Other names: Aestuariibacter aggregatus, Aestuariibacter aggregatus Wang et al. 2010, Alteromonas sp. WH169, CGMCC 1.8995, LMG 25283, LMG:25283, M. aggregata, Marisediminitalea aggregata (Wang et al. 2010) Zhang et al., strain WH169
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