node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HAH_1374 | nadE1 | HAH_1374 | HAH_2917 | ATP-NAD kinase. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.931 |
HAH_1374 | nadR | HAH_1374 | HAH_2424 | ATP-NAD kinase. | Nicotinamide-nucleotide adenylyltransferase. | 0.917 |
HAH_1374 | ppnK | HAH_1374 | HAH_0620 | ATP-NAD kinase. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.922 |
HAH_1374 | sir2 | HAH_1374 | HAH_1168 | ATP-NAD kinase. | Sir2 family transcriptional regulator / NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily. | 0.937 |
HAH_1374 | srp54 | HAH_1374 | HAH_0392 | ATP-NAD kinase. | Signal recognition 54 kDa protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.532 |
fps | ppnK | HAH_0412 | HAH_0620 | Farnesyl-pyrrophosphate synthase; Belongs to the FPP/GGPP synthase family. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.527 |
kaiC1 | ppnK | HAH_0621 | HAH_0620 | Circadian regulator. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.744 |
nadE1 | HAH_1374 | HAH_2917 | HAH_1374 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | ATP-NAD kinase. | 0.931 |
nadE1 | nadR | HAH_2917 | HAH_2424 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Nicotinamide-nucleotide adenylyltransferase. | 0.958 |
nadE1 | ppnK | HAH_2917 | HAH_0620 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.931 |
nadE1 | sir2 | HAH_2917 | HAH_1168 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Sir2 family transcriptional regulator / NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily. | 0.943 |
nadR | HAH_1374 | HAH_2424 | HAH_1374 | Nicotinamide-nucleotide adenylyltransferase. | ATP-NAD kinase. | 0.917 |
nadR | nadE1 | HAH_2424 | HAH_2917 | Nicotinamide-nucleotide adenylyltransferase. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.958 |
nadR | ppnK | HAH_2424 | HAH_0620 | Nicotinamide-nucleotide adenylyltransferase. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.917 |
nadR | sir2 | HAH_2424 | HAH_1168 | Nicotinamide-nucleotide adenylyltransferase. | Sir2 family transcriptional regulator / NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily. | 0.971 |
pdhD1 | pdhD3 | HAH_0213 | HAH_4312 | Dihydrolipoamide dehydrogenase. | Dihydrolipoamide dehydrogenase. | 0.902 |
pdhD1 | ppnK | HAH_0213 | HAH_0620 | Dihydrolipoamide dehydrogenase. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.546 |
pdhD2 | ppnK | HAH_0613 | HAH_0620 | Dihydrolipoamide dehydrogenase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.546 |
pdhD3 | pdhD1 | HAH_4312 | HAH_0213 | Dihydrolipoamide dehydrogenase. | Dihydrolipoamide dehydrogenase. | 0.902 |
pdhD3 | ppnK | HAH_4312 | HAH_0620 | Dihydrolipoamide dehydrogenase. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.546 |