Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
coxA2Cytochrome c oxidase subunit I. (333 aa)    
Predicted Functional Partners:
stt3
Transmembrane oligosaccharyl transferase.
  
   
 0.862
sec11a
Signal sequence peptidase.
  
   
 0.781
HAH_2955
Peptidase A24B, FlaK domain protein.
 
   
 0.775
sec11b
Signal sequence peptidase.
  
   
 0.774
HAH_4236
Sodium/hydrogen exchanger.
   
    0.757
HAH_1629
Conserved hypothetical protein.
  
     0.751
HAH_3103
Conserved hypothetical protein.
  
     0.745
rpaA1
Replication factor A.
  
     0.718
secE
Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
 
     0.713
htlB
HTR-like protein.
  
     0.712
Your Current Organism:
Haloarcula hispanica
NCBI taxonomy Id: 634497
Other names: H. hispanica ATCC 33960, Haloarcula hispanica ATCC 33960, Haloarcula hispanica DSM 4426, Haloarcula hispanica JCM 8911, Haloarcula hispanica str. ATCC 33960, Haloarcula hispanica strain ATCC 33960
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.