Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
aspB5Aspartate aminotransferase. (384 aa)    
Predicted Functional Partners:
ribH
Riboflavin synthase beta subunit (6,7-dimethyl-8-ribityllumazine synthase).
  
 
 0.975
mdhA
Malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.942
katG
Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
  
 
 0.936
metB
Cystathionine gamma-synthase.
  
 
 0.934
argG
Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 0.930
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 0.924
gadB
L-tyrosine decarboxylase.
  
 
 0.920
pheA2
Prephenate dehydratase.
  
 
 0.919
gdhA1
Glutamate dehydrogenase (NAD(P)+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.919
gdhA2
Glutamate dehydrogenase (NAD(P)+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.919
Your Current Organism:
Haloarcula hispanica
NCBI taxonomy Id: 634497
Other names: H. hispanica ATCC 33960, Haloarcula hispanica ATCC 33960, Haloarcula hispanica DSM 4426, Haloarcula hispanica JCM 8911, Haloarcula hispanica str. ATCC 33960, Haloarcula hispanica strain ATCC 33960
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