STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ham1Ham1 protein. (223 aa)    
Predicted Functional Partners:
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
  
 0.954
guaA2
GMP synthase subunit B; Catalyzes the synthesis of GMP from XMP.
 
 
 0.951
guaB2
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 0.944
guaA3
GMP synthase subunit A; Catalyzes the synthesis of GMP from XMP.
 
 
 0.931
guaA1
GMP synthase.
  
 
 0.919
surE
Acid phosphatase SurE / 5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.909
cpdB2
2',3'-cyclic-nucleotide 2'-phosphodiesterase.
  
 
  0.904
cpdB3
2',3'-cyclic-nucleotide 2'-phosphodiesterase / 5'-nucleotidase.
  
 
  0.904
gcp
O-sialoglycoprotein endopeptidase/protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family.
     
 0.819
thrS
threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.773
Your Current Organism:
Haloarcula hispanica
NCBI taxonomy Id: 634497
Other names: H. hispanica ATCC 33960, Haloarcula hispanica ATCC 33960, Haloarcula hispanica DSM 4426, Haloarcula hispanica JCM 8911, Haloarcula hispanica str. ATCC 33960, Haloarcula hispanica strain ATCC 33960
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