node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HAH_4188 | HAH_4399 | HAH_4188 | HAH_4399 | Conserved hypothetical protein. | Helicase domain protein. | 0.643 |
HAH_4188 | dnaN1 | HAH_4188 | HAH_0128 | Conserved hypothetical protein. | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.638 |
HAH_4188 | eif4A | HAH_4188 | HAH_3099 | Conserved hypothetical protein. | Hef nuclease / ATP-dependent RNA helicase-like protein eIF-4A. | 0.725 |
HAH_4188 | mcm | HAH_4188 | HAH_0050 | Conserved hypothetical protein. | Cell division control protein/MCM family protein. | 0.869 |
HAH_4188 | pri1 | HAH_4188 | HAH_0121 | Conserved hypothetical protein. | DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.640 |
HAH_4188 | radA | HAH_4188 | HAH_0176 | Conserved hypothetical protein. | DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | 0.654 |
HAH_4188 | radB | HAH_4188 | HAH_2104 | Conserved hypothetical protein. | DNA repair and recombination protein RadB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. | 0.654 |
HAH_4188 | rpl32E | HAH_4188 | HAH_2137 | Conserved hypothetical protein. | 50S ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family. | 0.654 |
HAH_4188 | topA | HAH_4188 | HAH_2187 | Conserved hypothetical protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.786 |
HAH_4188 | yhcR3 | HAH_4188 | HAH_2361 | Conserved hypothetical protein. | Phosphoesterase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity; Belongs to the MRE11/RAD32 family. | 0.797 |
HAH_4399 | HAH_4188 | HAH_4399 | HAH_4188 | Helicase domain protein. | Conserved hypothetical protein. | 0.643 |
HAH_4399 | dnaN1 | HAH_4399 | HAH_0128 | Helicase domain protein. | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.832 |
HAH_4399 | eif4A | HAH_4399 | HAH_3099 | Helicase domain protein. | Hef nuclease / ATP-dependent RNA helicase-like protein eIF-4A. | 0.651 |
HAH_4399 | mcm | HAH_4399 | HAH_0050 | Helicase domain protein. | Cell division control protein/MCM family protein. | 0.488 |
HAH_4399 | radA | HAH_4399 | HAH_0176 | Helicase domain protein. | DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | 0.715 |
HAH_4399 | radB | HAH_4399 | HAH_2104 | Helicase domain protein. | DNA repair and recombination protein RadB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. | 0.715 |
HAH_4399 | rpl32E | HAH_4399 | HAH_2137 | Helicase domain protein. | 50S ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family. | 0.856 |
HAH_4399 | topA | HAH_4399 | HAH_2187 | Helicase domain protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.753 |
HAH_4399 | yhcR3 | HAH_4399 | HAH_2361 | Helicase domain protein. | Phosphoesterase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity; Belongs to the MRE11/RAD32 family. | 0.800 |
dnaN1 | HAH_4188 | HAH_0128 | HAH_4188 | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | Conserved hypothetical protein. | 0.638 |