Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
eif2bTranslation initiation factor aIF-2 beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (135 aa)    
Predicted Functional Partners:
eif2g
Translation initiation factor aIF-2 gamma subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
  
 0.997
eif1a
Translation initiation factor aIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
 
 0.997
eif2a
Translation initiation factor aIF-2 alpha subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family.
  
 0.994
rps4e
Ribosomal protein S4e Rps4e; Belongs to the eukaryotic ribosomal protein eS4 family.
  
 0.986
rps6e
Ribosomal protein S6e Rps6e; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 0.985
rps15
Ribosomal protein S15P Rps15p.
  
 0.981
rps3ae
Ribosomal protein S3Ae Rps3ae; Belongs to the eukaryotic ribosomal protein eS1 family.
 
 0.978
rps17
Ribosomal protein S17P Rps17p; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
 
 0.978
rps3p
Ribosomal protein S3P Rps3p; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
  
 0.975
rps5p
Ribosomal protein S5P Rps5p; With S4 and S12 plays an important role in translational accuracy.
  
 0.967
Your Current Organism:
Methanobrevibacter ruminantium
NCBI taxonomy Id: 634498
Other names: M. ruminantium M1, Methanobrevibacter ruminantium M1, Methanobrevibacter ruminantium str. M1, Methanobrevibacter ruminantium strain M1
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