Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dfxDesulfoferrodoxin Dfx. (126 aa)    
Predicted Functional Partners:
mru_1257
Ferritin-like domain-containing protein.
  
  
 0.921
mru_0810
Glutamate synthase domain-containing protein; Belongs to the glutamate synthase family.
  
  
 0.771
fprA1
F420H2 oxidase FprA1.
  
 0.764
fprA2
F420H2 oxidase FprA2.
  
 0.736
mru_0467
Voltage-gated chloride channel protein.
 
     0.685
rbr1
Rubrerythrin Rbr1.
  
  
 0.662
rub1
Rubredoxin Rub1; Belongs to the rubredoxin family.
  
  
 0.659
rub2
Rubredoxin Rub2; Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.
  
  
 0.659
rub3
Rubredoxin Rub3; Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.
  
  
 0.659
uvrC
Excinuclease ABC C subunit UvrC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
      
 0.572
Your Current Organism:
Methanobrevibacter ruminantium
NCBI taxonomy Id: 634498
Other names: M. ruminantium M1, Methanobrevibacter ruminantium M1, Methanobrevibacter ruminantium str. M1, Methanobrevibacter ruminantium strain M1
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