Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ehbQEnergy-converting hydrogenase B subunit Q EhbQ. (219 aa)    
Predicted Functional Partners:
htpX
Peptidase M48 family; Belongs to the peptidase M48B family.
  
    0.876
hemD
uroporphyrinogen-III synthase HemD.
  
    0.800
alaS
alanyl-tRNA synthetase AlaS; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
 
    0.696
ehbP
Energy-converting hydrogenase B subunit P EhbP.
     
 0.696
mru_1504
Peptidase M48 family.
  
    0.676
mtd
F420-dependent methylenetetrahydromethanopterin dehydrogenase Mtd; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
  
     0.660
fwdG
Tungsten formylmethanofuran dehydrogenase subunit G FwdG.
 
     0.588
mru_1851
Methanogenesis marker protein 9.
  
     0.584
hypE1
Hydrogenase expression/formation protein HypE1.
  
     0.562
mru_2109
Methanogenesis marker protein 12; Belongs to the UPF0285 family.
  
     0.516
Your Current Organism:
Methanobrevibacter ruminantium
NCBI taxonomy Id: 634498
Other names: M. ruminantium M1, Methanobrevibacter ruminantium M1, Methanobrevibacter ruminantium str. M1, Methanobrevibacter ruminantium strain M1
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