Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
ehbKEnergy-converting hydrogenase B subunit K EhbK. (486 aa)    
Predicted Functional Partners:
ehbL
Energy-converting hydrogenase B subunit L EhbL.
 
  
 0.996
ehbI
Energy-converting hydrogenase B subunit I EhbI.
 
    0.984
ehbO
Energy-converting hydrogenase B subunit O EhbO.
 
  
 0.983
ehbG
Energy-converting hydrogenase B subunit G EhbG.
  
    0.964
ehbM
Energy-converting hydrogenase B subunit M EhbM.
  
  
 0.940
ehbH
Energy-converting hydrogenase B subunit H EhbH.
  
    0.919
ehbF
Energy-converting hydrogenase B subunit F EhbF.
 
   
 0.869
ehbE
Energy-converting hydrogenase B subunit E EhbE.
 
     0.817
ehbJ
Energy-converting hydrogenase B subunit J EhbJ.
       0.810
ehbD
Energy-converting hydrogenase B subunit D EhbD.
       0.758
Your Current Organism:
Methanobrevibacter ruminantium
NCBI taxonomy Id: 634498
Other names: M. ruminantium M1, Methanobrevibacter ruminantium M1, Methanobrevibacter ruminantium str. M1, Methanobrevibacter ruminantium strain M1
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