Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
argGArgininosuccinate synthase ArgG; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (391 aa)    
Predicted Functional Partners:
argH
Argininosuccinate lyase ArgH.
 
 
 0.999
argF
Ornithine carbamoyltransferase ArgF; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
 
 0.994
carB
Carbamoyl-phosphate synthase large subunit CarB; Belongs to the CarB family.
 
 
 0.992
asnB
Asparagine synthase (glutamine-hydrolyzing) AsnB.
  
 0.979
ask
Aspartate kinase Ask; Belongs to the aspartokinase family.
 
 
 0.977
argC
N-acetyl-gamma-glutamyl-phosphate reductase ArgC; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
  
 0.966
argB
Acetylglutamate kinase ArgB; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
  
 0.960
argD
Acetylornithine aminotransferase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 
 0.958
carA
Carbamoyl-phosphate synthase small subunit CarA; Belongs to the CarA family.
  
 
 0.951
purA
Adenylosuccinate synthetase PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.949
Your Current Organism:
Methanobrevibacter ruminantium
NCBI taxonomy Id: 634498
Other names: M. ruminantium M1, Methanobrevibacter ruminantium M1, Methanobrevibacter ruminantium str. M1, Methanobrevibacter ruminantium strain M1
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