node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EbC_05950 | EbC_44420 | EbC_05950 | EbC_44420 | Type VI secretion system ATPase, ClpV1 family protein; silverDB:661Eb00796; Belongs to the ClpA/ClpB family. | Heat shock protein; silverDB:661Eb05831; Belongs to the small heat shock protein (HSP20) family. | 0.707 |
EbC_05950 | Hspa4 | EbC_05950 | EbC_10470 | Type VI secretion system ATPase, ClpV1 family protein; silverDB:661Eb00796; Belongs to the ClpA/ClpB family. | Heat shock protein Hsp90 family protein; Molecular chaperone. Has ATPase activity. | 0.658 |
EbC_05950 | clpA | EbC_05950 | EbC_04110 | Type VI secretion system ATPase, ClpV1 family protein; silverDB:661Eb00796; Belongs to the ClpA/ClpB family. | Clp ATPase; silverDB:661Eb00544; Belongs to the ClpA/ClpB family. | 0.908 |
EbC_05950 | dnaK | EbC_05950 | EbC_06680 | Type VI secretion system ATPase, ClpV1 family protein; silverDB:661Eb00796; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK (Heat shock 70 kDa protein); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.908 |
EbC_05950 | grpE | EbC_05950 | EbC_34250 | Type VI secretion system ATPase, ClpV1 family protein; silverDB:661Eb00796; Belongs to the ClpA/ClpB family. | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...] | 0.716 |
EbC_05950 | hslU | EbC_05950 | EbC_01550 | Type VI secretion system ATPase, ClpV1 family protein; silverDB:661Eb00796; Belongs to the ClpA/ClpB family. | ATP-dependent hsl protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.566 |
EbC_05950 | hslV | EbC_05950 | EbC_01560 | Type VI secretion system ATPase, ClpV1 family protein; silverDB:661Eb00796; Belongs to the ClpA/ClpB family. | ATP-dependent protease HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.552 |
EbC_05950 | lon | EbC_05950 | EbC_10100 | Type VI secretion system ATPase, ClpV1 family protein; silverDB:661Eb00796; Belongs to the ClpA/ClpB family. | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.592 |
EbC_44420 | EbC_05950 | EbC_44420 | EbC_05950 | Heat shock protein; silverDB:661Eb05831; Belongs to the small heat shock protein (HSP20) family. | Type VI secretion system ATPase, ClpV1 family protein; silverDB:661Eb00796; Belongs to the ClpA/ClpB family. | 0.707 |
EbC_44420 | Hspa4 | EbC_44420 | EbC_10470 | Heat shock protein; silverDB:661Eb05831; Belongs to the small heat shock protein (HSP20) family. | Heat shock protein Hsp90 family protein; Molecular chaperone. Has ATPase activity. | 0.726 |
EbC_44420 | clpA | EbC_44420 | EbC_04110 | Heat shock protein; silverDB:661Eb05831; Belongs to the small heat shock protein (HSP20) family. | Clp ATPase; silverDB:661Eb00544; Belongs to the ClpA/ClpB family. | 0.707 |
EbC_44420 | clpA-2 | EbC_44420 | EbC_14840 | Heat shock protein; silverDB:661Eb05831; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease ATP-binding subunit ClpA; silverDB:661Eb01994; Belongs to the ClpA/ClpB family. | 0.707 |
EbC_44420 | clpB | EbC_44420 | EbC_34580 | Heat shock protein; silverDB:661Eb05831; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.707 |
EbC_44420 | dnaK | EbC_44420 | EbC_06680 | Heat shock protein; silverDB:661Eb05831; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein DnaK (Heat shock 70 kDa protein); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.659 |
EbC_44420 | grpE | EbC_44420 | EbC_34250 | Heat shock protein; silverDB:661Eb05831; Belongs to the small heat shock protein (HSP20) family. | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...] | 0.690 |
EbC_44420 | hslU | EbC_44420 | EbC_01550 | Heat shock protein; silverDB:661Eb05831; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent hsl protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.586 |
EbC_44420 | hslV | EbC_44420 | EbC_01560 | Heat shock protein; silverDB:661Eb05831; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent protease HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.630 |
EbC_44420 | lon | EbC_44420 | EbC_10100 | Heat shock protein; silverDB:661Eb05831; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.663 |
Hspa4 | EbC_05950 | EbC_10470 | EbC_05950 | Heat shock protein Hsp90 family protein; Molecular chaperone. Has ATPase activity. | Type VI secretion system ATPase, ClpV1 family protein; silverDB:661Eb00796; Belongs to the ClpA/ClpB family. | 0.658 |
Hspa4 | EbC_44420 | EbC_10470 | EbC_44420 | Heat shock protein Hsp90 family protein; Molecular chaperone. Has ATPase activity. | Heat shock protein; silverDB:661Eb05831; Belongs to the small heat shock protein (HSP20) family. | 0.726 |