| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| comL | lebB | Bgr_13890 | Bgr_05910 | Competence lipoprotein ComL precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.692 |
| comL | yidC | Bgr_13890 | Bgr_09380 | Competence lipoprotein ComL precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Preprotein translocase subunit YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.609 |
| era | lebB | Bgr_05930 | Bgr_05910 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.841 |
| era | lepA | Bgr_05930 | Bgr_00680 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.638 |
| era | panC | Bgr_05930 | Bgr_05950 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Pantoate-beta-alanine ligase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.624 |
| era | recO | Bgr_05930 | Bgr_05940 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.912 |
| era | rnc | Bgr_05930 | Bgr_05920 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.927 |
| era | spoT | Bgr_05930 | Bgr_05870 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.617 |
| lebB | comL | Bgr_05910 | Bgr_13890 | Signal peptidase I; Belongs to the peptidase S26 family. | Competence lipoprotein ComL precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.692 |
| lebB | era | Bgr_05910 | Bgr_05930 | Signal peptidase I; Belongs to the peptidase S26 family. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.841 |
| lebB | lepA | Bgr_05910 | Bgr_00680 | Signal peptidase I; Belongs to the peptidase S26 family. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.780 |
| lebB | panC | Bgr_05910 | Bgr_05950 | Signal peptidase I; Belongs to the peptidase S26 family. | Pantoate-beta-alanine ligase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.679 |
| lebB | recO | Bgr_05910 | Bgr_05940 | Signal peptidase I; Belongs to the peptidase S26 family. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.711 |
| lebB | rnc | Bgr_05910 | Bgr_05920 | Signal peptidase I; Belongs to the peptidase S26 family. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.898 |
| lebB | rnhB | Bgr_05910 | Bgr_04540 | Signal peptidase I; Belongs to the peptidase S26 family. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.704 |
| lebB | secD | Bgr_05910 | Bgr_07450 | Signal peptidase I; Belongs to the peptidase S26 family. | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.718 |
| lebB | spoT | Bgr_05910 | Bgr_05870 | Signal peptidase I; Belongs to the peptidase S26 family. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.713 |
| lebB | yidC | Bgr_05910 | Bgr_09380 | Signal peptidase I; Belongs to the peptidase S26 family. | Preprotein translocase subunit YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.712 |
| lepA | era | Bgr_00680 | Bgr_05930 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.638 |
| lepA | lebB | Bgr_00680 | Bgr_05910 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.780 |