| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bgr_19660 | cynT | Bgr_19660 | Bgr_19650 | NAD glutamate dehydrogenase. | Carbonic anhydrase protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | 0.460 |
| cynT | Bgr_19660 | Bgr_19650 | Bgr_19660 | Carbonic anhydrase protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | NAD glutamate dehydrogenase. | 0.460 |
| cynT | ffh | Bgr_19650 | Bgr_19640 | Carbonic anhydrase protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | 0.459 |
| cynT | guaB | Bgr_19650 | Bgr_01890 | Carbonic anhydrase protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.414 |
| cynT | macB | Bgr_19650 | Bgr_18970 | Carbonic anhydrase protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.448 |
| cynT | maeB1 | Bgr_19650 | Bgr_00990 | Carbonic anhydrase protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | Malic enzyme. | 0.415 |
| cynT | maeB2 | Bgr_19650 | Bgr_11560 | Carbonic anhydrase protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | Malic enzyme. | 0.415 |
| cynT | rpsP | Bgr_19650 | Bgr_19620 | Carbonic anhydrase protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.417 |
| cynT | tyrA | Bgr_19650 | Bgr_19630 | Carbonic anhydrase protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | Chorismate mutase. | 0.410 |
| ffh | cynT | Bgr_19640 | Bgr_19650 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | Carbonic anhydrase protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | 0.459 |
| ffh | macB | Bgr_19640 | Bgr_18970 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.455 |
| ffh | rpsP | Bgr_19640 | Bgr_19620 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.954 |
| ffh | tyrA | Bgr_19640 | Bgr_19630 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | Chorismate mutase. | 0.730 |
| guaB | cynT | Bgr_01890 | Bgr_19650 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Carbonic anhydrase protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | 0.414 |
| macB | cynT | Bgr_18970 | Bgr_19650 | ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Carbonic anhydrase protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | 0.448 |
| macB | ffh | Bgr_18970 | Bgr_19640 | ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | 0.455 |
| maeB1 | cynT | Bgr_00990 | Bgr_19650 | Malic enzyme. | Carbonic anhydrase protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | 0.415 |
| maeB1 | maeB2 | Bgr_00990 | Bgr_11560 | Malic enzyme. | Malic enzyme. | 0.949 |
| maeB1 | tyrA | Bgr_00990 | Bgr_19630 | Malic enzyme. | Chorismate mutase. | 0.526 |
| maeB2 | cynT | Bgr_11560 | Bgr_19650 | Malic enzyme. | Carbonic anhydrase protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | 0.415 |