STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADG80916.1Carboxyl-terminal protease; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; TIGRFAM: carboxyl-terminal protease; KEGG: cth:Cthe_1930 carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; Peptidoglycan-binding domain 1 protein; Belongs to the peptidase S41A family. (494 aa)    
Predicted Functional Partners:
ADG80913.1
Transcriptional regulator, GntR family; KEGG: drm:Dred_3243 regulatory protein GntR, HTH; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH.
       0.474
ADG80914.1
KEGG: drm:Dred_3242 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
       0.474
ADG80915.1
KEGG: nth:Nther_0730 hypothetical protein.
       0.474
ADG82569.1
KEGG: hmo:HM1_0282 oxaloacetate decarboxylase, alpha subunit; TIGRFAM: oxaloacetate decarboxylase alpha subunit; acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein.
  
    0.457
pheT
KEGG: drm:Dred_1620 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
   
 
 0.428
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
    0.425
ADG82223.1
TIGRFAM: membrane-associated zinc metalloprotease; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; KEGG: pth:PTH_1261 membrane-associated Zn-dependent protease 1; SMART: PDZ/DHR/GLGF domain protein.
 
  
 0.422
Your Current Organism:
Thermincola potens
NCBI taxonomy Id: 635013
Other names: T. potens JR, Thermincola potens JR, Thermincola potens str. JR, Thermincola potens strain JR, Thermincola sp. JR
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.