ADG81361.1 protein (Thermincola potens) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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Score

ADG81361.1

PFAM: Integrase catalytic region; Transposase-like Mu; KEGG: sth:STH2720 transposase. (464 aa)

Predicted Functional Partners:

ADG81362.1

0.928

ADG81436.1

0.696

ADG82330.1

0.696

ADG82732.1

0.696

ADG82849.1

0.696

ADG83324.1

0.696

ADG83481.1

0.696

ADG81359.1

0.642

ADG81360.1

0.642

murJ

0.475

Your Current Organism:

Thermincola potens

NCBI taxonomy Id: 635013
Other names: T. potens JR, Thermincola potens JR, Thermincola potens str. JR, Thermincola potens strain JR, Thermincola sp. JR

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADG81359.1	ADG81360.1	TherJR_0478	TherJR_0479	KEGG: sth:STH2721 hypothetical protein.	Hypothetical protein; KEGG: sai:Saci_1102 dehydrogenase.	0.773
ADG81359.1	ADG81361.1	TherJR_0478	TherJR_0480	KEGG: sth:STH2721 hypothetical protein.	PFAM: Integrase catalytic region; Transposase-like Mu; KEGG: sth:STH2720 transposase.	0.642
ADG81359.1	ADG81362.1	TherJR_0478	TherJR_0481	KEGG: sth:STH2721 hypothetical protein.	SMART: AAA ATPase; KEGG: chy:CHY_1252 ISChy3, orf3.	0.642
ADG81359.1	murJ	TherJR_0478	TherJR_0482	KEGG: sth:STH2721 hypothetical protein.	Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.	0.405
ADG81360.1	ADG81359.1	TherJR_0479	TherJR_0478	Hypothetical protein; KEGG: sai:Saci_1102 dehydrogenase.	KEGG: sth:STH2721 hypothetical protein.	0.773
ADG81360.1	ADG81361.1	TherJR_0479	TherJR_0480	Hypothetical protein; KEGG: sai:Saci_1102 dehydrogenase.	PFAM: Integrase catalytic region; Transposase-like Mu; KEGG: sth:STH2720 transposase.	0.642
ADG81360.1	ADG81362.1	TherJR_0479	TherJR_0481	Hypothetical protein; KEGG: sai:Saci_1102 dehydrogenase.	SMART: AAA ATPase; KEGG: chy:CHY_1252 ISChy3, orf3.	0.642
ADG81360.1	murJ	TherJR_0479	TherJR_0482	Hypothetical protein; KEGG: sai:Saci_1102 dehydrogenase.	Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.	0.405
ADG81361.1	ADG81359.1	TherJR_0480	TherJR_0478	PFAM: Integrase catalytic region; Transposase-like Mu; KEGG: sth:STH2720 transposase.	KEGG: sth:STH2721 hypothetical protein.	0.642
ADG81361.1	ADG81360.1	TherJR_0480	TherJR_0479	PFAM: Integrase catalytic region; Transposase-like Mu; KEGG: sth:STH2720 transposase.	Hypothetical protein; KEGG: sai:Saci_1102 dehydrogenase.	0.642
ADG81361.1	ADG81362.1	TherJR_0480	TherJR_0481	PFAM: Integrase catalytic region; Transposase-like Mu; KEGG: sth:STH2720 transposase.	SMART: AAA ATPase; KEGG: chy:CHY_1252 ISChy3, orf3.	0.928
ADG81361.1	ADG81436.1	TherJR_0480	TherJR_0559	PFAM: Integrase catalytic region; Transposase-like Mu; KEGG: sth:STH2720 transposase.	SMART: AAA ATPase; KEGG: chy:CHY_1252 ISChy3, orf3.	0.696
ADG81361.1	ADG82330.1	TherJR_0480	TherJR_1475	PFAM: Integrase catalytic region; Transposase-like Mu; KEGG: sth:STH2720 transposase.	SMART: AAA ATPase; KEGG: chy:CHY_1252 ISChy3, orf3.	0.696
ADG81361.1	ADG82732.1	TherJR_0480	TherJR_1883	PFAM: Integrase catalytic region; Transposase-like Mu; KEGG: sth:STH2720 transposase.	SMART: AAA ATPase; KEGG: chy:CHY_1252 ISChy3, orf3.	0.696
ADG81361.1	ADG82849.1	TherJR_0480	TherJR_2004	PFAM: Integrase catalytic region; Transposase-like Mu; KEGG: sth:STH2720 transposase.	SMART: AAA ATPase; KEGG: chy:CHY_1252 ISChy3, orf3.	0.696
ADG81361.1	ADG83324.1	TherJR_0480	TherJR_2487	PFAM: Integrase catalytic region; Transposase-like Mu; KEGG: sth:STH2720 transposase.	SMART: AAA ATPase; KEGG: chy:CHY_1252 ISChy3, orf3.	0.696
ADG81361.1	ADG83481.1	TherJR_0480	TherJR_2645	PFAM: Integrase catalytic region; Transposase-like Mu; KEGG: sth:STH2720 transposase.	SMART: AAA ATPase; KEGG: chy:CHY_1252 ISChy3, orf3.	0.696
ADG81361.1	murJ	TherJR_0480	TherJR_0482	PFAM: Integrase catalytic region; Transposase-like Mu; KEGG: sth:STH2720 transposase.	Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.	0.475
ADG81362.1	ADG81359.1	TherJR_0481	TherJR_0478	SMART: AAA ATPase; KEGG: chy:CHY_1252 ISChy3, orf3.	KEGG: sth:STH2721 hypothetical protein.	0.642
ADG81362.1	ADG81360.1	TherJR_0481	TherJR_0479	SMART: AAA ATPase; KEGG: chy:CHY_1252 ISChy3, orf3.	Hypothetical protein; KEGG: sai:Saci_1102 dehydrogenase.	0.642

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Network Stats

number of nodes:

11

number of edges:

28

average node degree:

5.09

avg. local clustering coefficient:

0.819

expected number of edges:

11

PPI enrichment p-value:

1.52e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

10 of 115

1.52

2.95

5.62e-12

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

10 of 52

1.86

4.93

1.91e-15

GO:0019843

rRNA binding

7 of 40

1.82

3.46

1.08e-09

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

10 of 58

1.81

4.77

9.37e-16

GO:0044391

Ribosomal subunit

4 of 15

2.0

2.67

2.10e-06

GO:0015934

Large ribosomal subunit

3 of 8

2.15

2.25

3.51e-05

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:36090071

(2022) Characterization and genomic analysis of two novel psychrotolerant Acidithiobacillus ferrooxidans strains from polar and subpolar environments.

5 of 31

1.78

2.58

6.98e-07

PMID:34412707

(2021) The metabolic footprint of Clostridia and Erysipelotrichia reveals their role in depleting sugar alcohols in the cecum.

2 of 11

1.84

1.01

0.0105

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:235

Large ribosomal subunit, and Structural constituent of ribosome

9 of 17

2.3

7.23

3.54e-17

CL:229

rRNA-binding, and Elongation Factor G, domain II

10 of 30

2.1

6.5

1.85e-17

CL:226

Structural constituent of ribosome, and Translation regulator activity

11 of 64

1.81

5.06

1.85e-17

CL:256

Mixed, incl. Large ribosomal subunit, and KOW (Kyprides, Ouzounis, Woese) motif.

5 of 6

2.5

4.6

9.61e-10

CL:237

Mixed, incl. Large ribosomal subunit, and KOW

3 of 7

2.21

2.13

7.26e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

10 of 58

1.81

4.77

9.60e-16

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

7 of 42

1.8

3.35

1.84e-09

GOCC:0015934

Large ribosomal subunit

4 of 9

2.22

3.05

7.63e-07

GOCC:0044391

Ribosomal subunit

5 of 22

1.93

2.94

2.50e-07

GOCC:0022626

Cytosolic ribosome

4 of 19

1.9

2.37

7.25e-06

GOCC:0022625

Cytosolic large ribosomal subunit

3 of 6

2.28

2.32

3.27e-05

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

9 of 50

1.83

4.42

1.47e-13

KW-0699

rRNA-binding

7 of 38

1.84

3.69

2.52e-10

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00739

KOW (Kyprides, Ouzounis, Woese) motif.

2 of 3

2.4

1.15

0.0077

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