STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADG81766.1Site-specific DNA-methyltransferase (adenine-specific); KEGG: dol:Dole_2236 N-6 DNA methylase; PFAM: N-6 DNA methylase. (518 aa)    
Predicted Functional Partners:
ADG81767.1
PFAM: restriction modification system DNA specificity domain; KEGG: net:Neut_0540 restriction modification system DNA specificity subunit.
 
 
 0.997
ADG81768.1
Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
 
 0.996
ADG81765.1
KEGG: hmo:HM1_2860 subtilisin-like protease.
 
   
 0.613
ADG81764.1
KEGG: hmo:HM1_2861 ATPase, aaa family; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase.
       0.510
ADG81934.1
KEGG: ctc:CTC00689 hypothetical protein.
  
   0.457
ADG81763.1
KEGG: dde:Dde_2500 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
  
  
 0.445
ADG81312.1
PFAM: SMC domain protein; KEGG: ami:Amir_5288 SMC domain protein.
  
  
 0.425
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.422
Your Current Organism:
Thermincola potens
NCBI taxonomy Id: 635013
Other names: T. potens JR, Thermincola potens JR, Thermincola potens str. JR, Thermincola potens strain JR, Thermincola sp. JR
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.