STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (358 aa)    
Predicted Functional Partners:
ADG82761.1
KEGG: mta:Moth_1651 nitrogen-fixing NifU-like; TIGRFAM: FeS cluster assembly scaffold protein NifU; PFAM: nitrogen-fixing NifU domain protein.
 
  
 0.980
iscS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
 
  
 0.939
ADG82763.1
KEGG: dae:Dtox_2275 transcriptional regulator, BadM/Rrf2 family; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074.
  
  
 0.789
ADG83828.1
PFAM: Queuosine synthesis-like; KEGG: chy:CHY_1281 hypothetical protein.
    
 0.745
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.704
mnmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
 
 0.675
ADG82238.1
KEGG: pth:PTH_1273 FAD synthase; TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: FAD synthetase; Riboflavin kinase; Belongs to the ribF family.
 
    0.649
ADG82757.1
KEGG: pth:PTH_1057 hypothetical protein.
       0.617
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
 
 
 
 0.611
ADG82758.1
KEGG: dge:Dgeo_1677 PRC-barrel domain-containing protein; manually curated; PFAM: PRC-barrel domain protein.
       0.604
Your Current Organism:
Thermincola potens
NCBI taxonomy Id: 635013
Other names: T. potens JR, Thermincola potens JR, Thermincola potens str. JR, Thermincola potens strain JR, Thermincola sp. JR
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.