Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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nnrECarbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] (533 aa)    
Predicted Functional Partners:
ACC83006.1
PFAM: NUDIX hydrolase; KEGG: ava:Ava_0948 NUDIX hydrolase.
 
 0.806
ACC84863.1
PFAM: NUDIX hydrolase; KEGG: ava:Ava_3513 NUDIX hydrolase.
 
 0.792
ACC84027.1
PFAM: NUDIX hydrolase; KEGG: fal:FRAAL1512 putative NUDIX hydrolase.
  
 0.760
ACC82452.1
KEGG: ava:Ava_4306 hypothetical protein.
  
 0.748
ACC82881.1
PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: ava:Ava_0642 DEAD/DEAH box helicase-like; Belongs to the DEAD box helicase family.
  
 0.739
ACC81991.1
PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: ava:Ava_1952 DEAD/DEAH box helicase-like; Belongs to the DEAD box helicase family.
  
 0.739
ACC84592.1
PFAM: helicase domain protein; KEGG: ava:Ava_C0236 helicase-like.
  
 0.738
ACC84236.1
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; KEGG: ana:all0945 succinate dehydrogenase iron-sulfur protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
  
 0.729
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
   0.723
groL-2
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
   0.723
Your Current Organism:
Nostoc punctiforme
NCBI taxonomy Id: 63737
Other names: N. punctiforme PCC 73102, Nostoc punctiforme ATCC 29133, Nostoc punctiforme PCC 73102, Nostoc sp. (strain ATCC 29133 / PCC 73102), Nostoc sp. ATCC 29133, Nostoc sp. PCC 73102
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