STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACC83905.13-dehydroquinate synthase; Catalyzes the conversion of sedoheptulose 7-phosphate to demethyl-4-deoxygadusol (DDG). Involved in the synthesis of the mycosporine-like amino acid shinorine, a natural sunscreen compound that protects the cell against UV radiation. (410 aa)    
Predicted Functional Partners:
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
 0.970
ACC83904.1
PFAM: O-methyltransferase, family 3; KEGG: ter:Tery_2976 caffeoyl-CoA O-methyltransferase.
   
 0.959
ACC83903.1
KEGG: ava:Ava_3856 hypothetical protein.
   
 0.933
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
  
 0.926
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.834
ACC82073.1
PFAM: O-methyltransferase, family 3; KEGG: ava:Ava_1652 O-methyltransferase, family 3.
    
 0.710
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
 0.709
ACC79770.1
TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: ava:Ava_0861 3-deoxy-7-phosphoheptulonate synthase.
 
  
 0.563
ACC79981.1
TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: ana:all0408 phospho-2-dehydro-3-deoxyheptonate aldolase.
 
  
 0.559
ACC79477.1
TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: ana:all0747 phospho-2-dehydro-3-deoxyheptonate aldolase / chorismate mutase.
 
  
 0.557
Your Current Organism:
Nostoc punctiforme
NCBI taxonomy Id: 63737
Other names: N. punctiforme PCC 73102, Nostoc punctiforme ATCC 29133, Nostoc punctiforme PCC 73102, Nostoc sp. (strain ATCC 29133 / PCC 73102), Nostoc sp. ATCC 29133, Nostoc sp. PCC 73102
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