node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SVI_2828 | gloA | SVI_2828 | SVI_2343 | Metallo-beta-lactamase family protein. | Lactoylglutathione lyase. | 0.915 |
SVI_2828 | gloB | SVI_2828 | SVI_2388 | Metallo-beta-lactamase family protein. | Hydroxyacylglutathione hydrolase, putative; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | 0.908 |
gloA | SVI_2828 | SVI_2343 | SVI_2828 | Lactoylglutathione lyase. | Metallo-beta-lactamase family protein. | 0.915 |
gloA | gloB | SVI_2343 | SVI_2388 | Lactoylglutathione lyase. | Hydroxyacylglutathione hydrolase, putative; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | 0.968 |
gloA | gor | SVI_2343 | SVI_0136 | Lactoylglutathione lyase. | Glutathione reductase. | 0.571 |
gloA | ilvA | SVI_2343 | SVI_3864 | Lactoylglutathione lyase. | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.815 |
gloA | nuoCD | SVI_2343 | SVI_1642 | Lactoylglutathione lyase. | NADH dehydrogenase I, C/D subunits; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.543 |
gloA | sdaA-1 | SVI_2343 | SVI_0703 | Lactoylglutathione lyase. | L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.800 |
gloA | sdaA-2 | SVI_2343 | SVI_2766 | Lactoylglutathione lyase. | L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.800 |
gloA | smpB | SVI_2343 | SVI_1353 | Lactoylglutathione lyase. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.552 |
gloA | trpA | SVI_2343 | SVI_2808 | Lactoylglutathione lyase. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.800 |
gloA | trpB | SVI_2343 | SVI_2807 | Lactoylglutathione lyase. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.815 |
gloB | SVI_2828 | SVI_2388 | SVI_2828 | Hydroxyacylglutathione hydrolase, putative; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | Metallo-beta-lactamase family protein. | 0.908 |
gloB | gloA | SVI_2388 | SVI_2343 | Hydroxyacylglutathione hydrolase, putative; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | Lactoylglutathione lyase. | 0.968 |
gor | gloA | SVI_0136 | SVI_2343 | Glutathione reductase. | Lactoylglutathione lyase. | 0.571 |
gor | nuoCD | SVI_0136 | SVI_1642 | Glutathione reductase. | NADH dehydrogenase I, C/D subunits; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.639 |
ilvA | gloA | SVI_3864 | SVI_2343 | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Lactoylglutathione lyase. | 0.815 |
ilvA | sdaA-1 | SVI_3864 | SVI_0703 | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.923 |
ilvA | sdaA-2 | SVI_3864 | SVI_2766 | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.923 |
ilvA | trpA | SVI_3864 | SVI_2808 | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.938 |