node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SVI_2017 | fumC | SVI_2017 | SVI_0395 | Fumarate hydratase, class I, anaerobic, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.967 |
SVI_2017 | sdhA | SVI_2017 | SVI_2737 | Fumarate hydratase, class I, anaerobic, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate dehydrogenase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.996 |
SVI_2017 | sdhB | SVI_2017 | SVI_2736 | Fumarate hydratase, class I, anaerobic, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate dehydrogenase, iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.991 |
SVI_2017 | sdhC | SVI_2017 | SVI_2739 | Fumarate hydratase, class I, anaerobic, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate dehydrogenase, cytochrome b556 subunit. | 0.978 |
SVI_2017 | sdhD | SVI_2017 | SVI_2738 | Fumarate hydratase, class I, anaerobic, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.978 |
SVI_2017 | sucA | SVI_2017 | SVI_2735 | Fumarate hydratase, class I, anaerobic, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 2-oxoglutarate dehydrogenase, E1 component. | 0.769 |
SVI_2017 | sucC | SVI_2017 | SVI_2733 | Fumarate hydratase, class I, anaerobic, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | succinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.686 |
SVI_2017 | sucD | SVI_2017 | SVI_2732 | Fumarate hydratase, class I, anaerobic, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | succinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.601 |
fumC | SVI_2017 | SVI_0395 | SVI_2017 | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Fumarate hydratase, class I, anaerobic, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.967 |
fumC | nuoCD | SVI_0395 | SVI_1642 | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | NADH dehydrogenase I, C/D subunits; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.790 |
fumC | nuoE | SVI_0395 | SVI_1641 | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | NADH dehydrogenase I, E subunit. | 0.401 |
fumC | sdhA | SVI_0395 | SVI_2737 | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Succinate dehydrogenase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.992 |
fumC | sdhB | SVI_0395 | SVI_2736 | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Succinate dehydrogenase, iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.970 |
fumC | sdhC | SVI_0395 | SVI_2739 | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Succinate dehydrogenase, cytochrome b556 subunit. | 0.964 |
fumC | sdhD | SVI_0395 | SVI_2738 | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.920 |
fumC | sucA | SVI_0395 | SVI_2735 | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 2-oxoglutarate dehydrogenase, E1 component. | 0.538 |
fumC | sucC | SVI_0395 | SVI_2733 | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | succinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.620 |
fumC | sucD | SVI_0395 | SVI_2732 | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | succinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.741 |
nuoCD | fumC | SVI_1642 | SVI_0395 | NADH dehydrogenase I, C/D subunits; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.790 |
nuoCD | nuoE | SVI_1642 | SVI_1641 | NADH dehydrogenase I, C/D subunits; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | NADH dehydrogenase I, E subunit. | 0.999 |