STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
puuDGamma-glutamyl-gamma-aminobutyrate hydrolase. (254 aa)    
Predicted Functional Partners:
puuC
Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 
  0.948
puuB
Gamma-glutamylputrescine oxidoreductase.
 
  
 0.932
puuR
Transcriptional regulator of the polyamine metabolism genes.
 
  
 0.916
ydcW
Gamma-aminobutyraldehyde dehydrogenase; Catalyzes the oxidation 4-aminobutanal (gamma- aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4- aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
  
 
  0.908
glnA
Glutamine synthetase.
  
 
 0.902
puuA
Gamma-glutamylputrescine synthetase; Belongs to the glutamine synthetase family.
 
  
 0.890
puuE
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.879
gltB
Glutamate synthase [NADPH] large subunit.
    
  0.821
putA
Bifunctional protein PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
     
  0.800
gdhA
NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
  0.800
Your Current Organism:
Citrobacter rodentium
NCBI taxonomy Id: 637910
Other names: C. rodentium ICC168, Citrobacter rodentium ICC168, Citrobacter rodentium str. ICC168, Citrobacter rodentium strain ICC168
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