close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
narXNitrate/nitrite two-component sensor kinase. (598 aa)    
Predicted Functional Partners:
narL
Nitrate/nitrite two-component response regulator.
 
 0.999
narP
Nitrate/nitrite response regulator protein.
 
 
 0.933
narK
Nitrite extrusion protein.
 
  
 0.743
uhpA
Two-component system response regulator protein.
 
 
 0.740
uhpA-2
Two-component system response regulator.
 
 
 0.701
ROD_42891
Conserved hypothetical protein (pseudogene); Pseudogene, truncated by two frameshift mutations.
 
 
 0.694
uvrY
Response regulator.
 
 
 0.607
csgD
Probable CsgAB operon transcriptional regulator.
 
 
 0.606
rcsB
Regulator of capsule synthesis (two-component system response regulator); Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
 
 
 0.575
dcuR
Two-component response regulator.
  
   
 0.565
Your Current Organism:
Citrobacter rodentium
NCBI taxonomy Id: 637910
Other names: C. rodentium ICC168, Citrobacter rodentium ICC168, Citrobacter rodentium str. ICC168, Citrobacter rodentium strain ICC168
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.