node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ROD_46831 | ROD_46851 | ROD_46831 | ROD_46851 | Putative phospholipid-binding protein. | Conserved hypothetical protein; Belongs to the UPF0102 family. | 0.768 |
ROD_46831 | diaA | ROD_46831 | ROD_46841 | Putative phospholipid-binding protein. | DnaA initiator-associating factor for replication initiation (putative phophosugar-binding protein); Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | 0.859 |
ROD_46831 | lpoA | ROD_46831 | ROD_46861 | Putative phospholipid-binding protein. | Putative lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family. | 0.763 |
ROD_46851 | ROD_46831 | ROD_46851 | ROD_46831 | Conserved hypothetical protein; Belongs to the UPF0102 family. | Putative phospholipid-binding protein. | 0.768 |
ROD_46851 | diaA | ROD_46851 | ROD_46841 | Conserved hypothetical protein; Belongs to the UPF0102 family. | DnaA initiator-associating factor for replication initiation (putative phophosugar-binding protein); Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | 0.800 |
ROD_46851 | lpoA | ROD_46851 | ROD_46861 | Conserved hypothetical protein; Belongs to the UPF0102 family. | Putative lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family. | 0.815 |
diaA | ROD_46831 | ROD_46841 | ROD_46831 | DnaA initiator-associating factor for replication initiation (putative phophosugar-binding protein); Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | Putative phospholipid-binding protein. | 0.859 |
diaA | ROD_46851 | ROD_46841 | ROD_46851 | DnaA initiator-associating factor for replication initiation (putative phophosugar-binding protein); Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | Conserved hypothetical protein; Belongs to the UPF0102 family. | 0.800 |
diaA | gmhB | ROD_46841 | ROD_02101 | DnaA initiator-associating factor for replication initiation (putative phophosugar-binding protein); Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | D,D-heptose 1,7-bisphosphate phosphatase. | 0.968 |
diaA | hisB | ROD_46841 | ROD_21601 | DnaA initiator-associating factor for replication initiation (putative phophosugar-binding protein); Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | Histidine biosynthesis bifunctional protein includes histidinol-phosphatase; imidazoleglycerol-phosphat dehydratase]. | 0.826 |
diaA | hldE | ROD_46841 | ROD_35951 | DnaA initiator-associating factor for replication initiation (putative phophosugar-binding protein); Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | Bifunctional protein HldE [includes: D-beta-D-heptose 7-phosphate kinase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 0.872 |
diaA | lpoA | ROD_46841 | ROD_46861 | DnaA initiator-associating factor for replication initiation (putative phophosugar-binding protein); Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | Putative lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family. | 0.784 |
diaA | rfaC | ROD_46841 | ROD_41961 | DnaA initiator-associating factor for replication initiation (putative phophosugar-binding protein); Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | Lipopolysaccharide heptosyltransferase 1. | 0.669 |
diaA | rfaD | ROD_46841 | ROD_41981 | DnaA initiator-associating factor for replication initiation (putative phophosugar-binding protein); Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.735 |
diaA | rfaF | ROD_46841 | ROD_41971 | DnaA initiator-associating factor for replication initiation (putative phophosugar-binding protein); Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | ADP-heptose-LPS heptosyltransferase II. | 0.754 |
diaA | rfaQ | ROD_46841 | ROD_41851 | DnaA initiator-associating factor for replication initiation (putative phophosugar-binding protein); Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | heptosyl-III-transferase. | 0.740 |
gmhB | diaA | ROD_02101 | ROD_46841 | D,D-heptose 1,7-bisphosphate phosphatase. | DnaA initiator-associating factor for replication initiation (putative phophosugar-binding protein); Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily. | 0.968 |
gmhB | hldE | ROD_02101 | ROD_35951 | D,D-heptose 1,7-bisphosphate phosphatase. | Bifunctional protein HldE [includes: D-beta-D-heptose 7-phosphate kinase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 0.993 |
gmhB | rfaC | ROD_02101 | ROD_41961 | D,D-heptose 1,7-bisphosphate phosphatase. | Lipopolysaccharide heptosyltransferase 1. | 0.860 |
gmhB | rfaD | ROD_02101 | ROD_41981 | D,D-heptose 1,7-bisphosphate phosphatase. | ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.760 |