node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEW37136.1 | EEW37597.1 | HMPREF0444_1354 | HMPREF0444_0687 | CamS sex pheromone family protein; COG: COG4851; Pfam: PF07537; InterPro: IPR011426. | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | 0.611 |
EEW37136.1 | EEW37922.1 | HMPREF0444_1354 | HMPREF0444_0166 | CamS sex pheromone family protein; COG: COG4851; Pfam: PF07537; InterPro: IPR011426. | Hypothetical protein; COG: COG3906; Pfam: PF06949; InterPro: IPR009711; Belongs to the UPF0473 family. | 0.679 |
EEW37136.1 | EEW38088.1 | HMPREF0444_1354 | HMPREF0444_0332 | CamS sex pheromone family protein; COG: COG4851; Pfam: PF07537; InterPro: IPR011426. | DivIVA domain protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | 0.682 |
EEW37136.1 | dnaB | HMPREF0444_1354 | HMPREF0444_0860 | CamS sex pheromone family protein; COG: COG4851; Pfam: PF07537; InterPro: IPR011426. | Replication initiation and membrane attachment protein; Pfam: PF07261; InterPro: IPR010833. | 0.695 |
EEW37136.1 | ezrA | HMPREF0444_1354 | HMPREF0444_0157 | CamS sex pheromone family protein; COG: COG4851; Pfam: PF07537; InterPro: IPR011426. | Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | 0.723 |
EEW37136.1 | fstQ | HMPREF0444_1354 | HMPREF0444_0676 | CamS sex pheromone family protein; COG: COG4851; Pfam: PF07537; InterPro: IPR011426. | Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | 0.633 |
EEW37136.1 | pbp | HMPREF0444_1354 | HMPREF0444_0823 | CamS sex pheromone family protein; COG: COG4851; Pfam: PF07537; InterPro: IPR011426. | Penicillin-binding protein, transpeptidase domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR001460. | 0.748 |
EEW37136.1 | rpoE | HMPREF0444_1354 | HMPREF0444_1348 | CamS sex pheromone family protein; COG: COG4851; Pfam: PF07537; InterPro: IPR011426. | DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | 0.428 |
EEW37597.1 | EEW37136.1 | HMPREF0444_0687 | HMPREF0444_1354 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | CamS sex pheromone family protein; COG: COG4851; Pfam: PF07537; InterPro: IPR011426. | 0.611 |
EEW37597.1 | EEW37922.1 | HMPREF0444_0687 | HMPREF0444_0166 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | Hypothetical protein; COG: COG3906; Pfam: PF06949; InterPro: IPR009711; Belongs to the UPF0473 family. | 0.667 |
EEW37597.1 | EEW38088.1 | HMPREF0444_0687 | HMPREF0444_0332 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | DivIVA domain protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | 0.754 |
EEW37597.1 | dnaB | HMPREF0444_0687 | HMPREF0444_0860 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | Replication initiation and membrane attachment protein; Pfam: PF07261; InterPro: IPR010833. | 0.675 |
EEW37597.1 | ezrA | HMPREF0444_0687 | HMPREF0444_0157 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | 0.762 |
EEW37597.1 | fstQ | HMPREF0444_0687 | HMPREF0444_0676 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | 0.746 |
EEW37597.1 | pbp | HMPREF0444_0687 | HMPREF0444_0823 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | Penicillin-binding protein, transpeptidase domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR001460. | 0.565 |
EEW37597.1 | rpoE | HMPREF0444_0687 | HMPREF0444_1348 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | 0.640 |
EEW37920.1 | EEW37921.1 | HMPREF0444_0164 | HMPREF0444_0165 | Hypothetical protein; COG: COG4472; Pfam: PF06135; InterPro: IPR009309; Belongs to the UPF0297 family. | RNAse H domain protein, YqgF family; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | 0.972 |
EEW37920.1 | EEW37922.1 | HMPREF0444_0164 | HMPREF0444_0166 | Hypothetical protein; COG: COG4472; Pfam: PF06135; InterPro: IPR009309; Belongs to the UPF0297 family. | Hypothetical protein; COG: COG3906; Pfam: PF06949; InterPro: IPR009711; Belongs to the UPF0473 family. | 0.914 |
EEW37921.1 | EEW37920.1 | HMPREF0444_0165 | HMPREF0444_0164 | RNAse H domain protein, YqgF family; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | Hypothetical protein; COG: COG4472; Pfam: PF06135; InterPro: IPR009309; Belongs to the UPF0297 family. | 0.972 |
EEW37921.1 | EEW37922.1 | HMPREF0444_0165 | HMPREF0444_0166 | RNAse H domain protein, YqgF family; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | Hypothetical protein; COG: COG3906; Pfam: PF06949; InterPro: IPR009711; Belongs to the UPF0473 family. | 0.921 |