STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
queERadical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (248 aa)    
Predicted Functional Partners:
queD
Queuosine biosynthesis protein QueD; COG: COG0720; Pfam: PF01242; InterPro: IPR007115.
 
 
 0.999
queC
Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
 
 
 0.998
queF
preQ(1) synthase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
 
  
 0.916
nrdD
Anaerobic ribonucleoside-triphosphate reductase; COG: COG1328; Pfam: PF03477; InterPro: IPR012833.
  
 
 0.852
EEQ48191.1
Hypothetical protein.
  
 
 0.763
EEQ49598.1
Glycosyltransferase, group 2 family protein; Pfam: PF00535; InterPro: IPR001173.
       0.664
folE
Putative GTP cyclohydrolase I; COG: COG0302; Pfam: PF01227; InterPro: IPR001474.
  
  
 0.663
pssA
CDP-diacylglycerol-serine O-phosphatidyltransferase; COG: COG1183; Pfam: PF01066; InterPro: IPR004533; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
    0.659
psd
Phosphatidylserine decarboxylase; COG: COG0688; Pfam: PF02666; InterPro: IPR004428.
       0.653
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.618
Your Current Organism:
Selenomonas flueggei
NCBI taxonomy Id: 638302
Other names: S. flueggei ATCC 43531, Selenomonas flueggei ATCC 43531, Selenomonas flueggei str. ATCC 43531, Selenomonas flueggei strain ATCC 43531
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