STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
EEQ48958.1Putative ATP-dependent nuclease subunit B; ATP-dependent DNA helicase. (1198 aa)    
Predicted Functional Partners:
addA
ATP-dependent nuclease subunit A; ATP-dependent DNA helicase.
 
 
 0.999
sbcD
Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
  
 0.905
sbcC
Putative DNA sulfur modification protein DndD; COG: COG0419; Pfam: PF02463.
 
  
 0.890
EEQ48109.1
Hypothetical protein; COG: COG2384; Pfam: PF04816; InterPro: IPR006901.
 
     0.669
pcrA
ATP-dependent DNA helicase PcrA; COG: COG0210; Pfam: PF00580; InterPro: IPR005751.
     
 0.633
ligA
DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
     
 0.626
EEQ48960.1
Histidine triad domain protein; COG: COG0537; Pfam: PF01230; InterPro: IPR011151.
       0.578
EEQ49117.1
DEAD/DEAH box helicase; COG: COG0514; Pfam: PF00270,PF00271; InterPro: IPR004589.
     
 0.573
ppaC
DHHA2 domain protein; COG: COG1227; Pfam: PF01368,PF00571,PF07085,PF02833; InterPro: IPR000644.
       0.559
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
  
     0.437
Your Current Organism:
Selenomonas flueggei
NCBI taxonomy Id: 638302
Other names: S. flueggei ATCC 43531, Selenomonas flueggei ATCC 43531, Selenomonas flueggei str. ATCC 43531, Selenomonas flueggei strain ATCC 43531
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