STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Thal_0200Succinate--CoA ligase (ADP-forming); KEGG: ppd:Ppro_1715 succinyl-CoA synthetase, alpha subunit; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase. (341 aa)    
Predicted Functional Partners:
Thal_0201
Succinate--CoA ligase (ADP-forming); KEGG: rcm:A1E_03180 succinyl-CoA synthetase subunit beta; PFAM: ATP-grasp domain protein.
 0.999
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
Thal_1455
KEGG: reu:Reut_C6294 citrate synthase.
 0.984
nuoC
NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
  
 
 0.930
nuoC-2
NADH-ubiquinone oxidoreductase chain 49kDa; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
  
 
 0.930
Thal_0289
KEGG: nam:NAMH_1126 fumarate reductase flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; HI0933 family protein.
 
 
 0.823
Thal_1402
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: nis:NIS_0010 succinate dehydrogenase/fumarate reductase, iron-sulfur protein.
 
 
 0.819
Thal_1165
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: gme:Gmet_0309 succinate dehydrogenase subunit B; PFAM: ferredoxin.
 
 
 0.814
Thal_0559
PFAM: H+transporting two-sector ATPase delta (OSCP) subunit; KEGG: gem:GM21_4038 ATP synthase F1, delta subunit.
   
 
 0.795
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.790
Your Current Organism:
Thermocrinis albus
NCBI taxonomy Id: 638303
Other names: T. albus DSM 14484, Thermocrinis albus DSM 14484, Thermocrinis albus HI 11/12, Thermocrinis albus str. DSM 14484, Thermocrinis albus strain DSM 14484
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.