node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BAI81306.1 | purC | DEFDS_1851 | DEFDS_1861 | Conserved hypothetical protein. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.951 |
BAI81306.1 | purD | DEFDS_1851 | DEFDS_1188 | Conserved hypothetical protein. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.945 |
BAI81306.1 | purE | DEFDS_1851 | DEFDS_1189 | Conserved hypothetical protein. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.951 |
BAI81306.1 | purF | DEFDS_1851 | DEFDS_1603 | Conserved hypothetical protein. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.951 |
BAI81306.1 | purH | DEFDS_1851 | DEFDS_1187 | Conserved hypothetical protein. | Bifunctional purine biosynthesis protein PurH; Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 0.951 |
BAI81306.1 | purL | DEFDS_1851 | DEFDS_1604 | Conserved hypothetical protein. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.951 |
BAI81306.1 | purM | DEFDS_1851 | DEFDS_0167 | Conserved hypothetical protein. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.950 |
BAI81306.1 | purN | DEFDS_1851 | DEFDS_0168 | Conserved hypothetical protein. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.950 |
BAI81306.1 | purQ | DEFDS_1851 | DEFDS_1605 | Conserved hypothetical protein. | Phosphoribosylformylglycinamidine synthase, large subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is though [...] | 0.951 |
BAI81306.1 | purS | DEFDS_1851 | DEFDS_1606 | Conserved hypothetical protein. | Phosphoribosylformylglycinamidine synthase, small subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is though [...] | 0.930 |
purC | BAI81306.1 | DEFDS_1861 | DEFDS_1851 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Conserved hypothetical protein. | 0.951 |
purC | purD | DEFDS_1861 | DEFDS_1188 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.996 |
purC | purE | DEFDS_1861 | DEFDS_1189 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.996 |
purC | purF | DEFDS_1861 | DEFDS_1603 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.957 |
purC | purH | DEFDS_1861 | DEFDS_1187 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Bifunctional purine biosynthesis protein PurH; Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 0.967 |
purC | purL | DEFDS_1861 | DEFDS_1604 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.956 |
purC | purM | DEFDS_1861 | DEFDS_0167 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.951 |
purC | purN | DEFDS_1861 | DEFDS_0168 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.964 |
purC | purQ | DEFDS_1861 | DEFDS_1605 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase, large subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is though [...] | 0.951 |
purC | purS | DEFDS_1861 | DEFDS_1606 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase, small subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is though [...] | 0.949 |