STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Snov_01574-hydroxyproline epimerase; Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). May be involved in a degradation pathway of t4LHyp, which would allow S.novella to grow on t4LHyp as a sole carbon source. (333 aa)    
Predicted Functional Partners:
Snov_0158
PFAM: FAD dependent oxidoreductase; KEGG: bmc:BAbS19_I16830 TrkA potassium uptake protein.
 
   
 0.938
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
    
 0.912
Snov_0159
PFAM: dihydrodipicolinate synthetase; KEGG: mlo:mll3981 dihydrodipicolinate synthase; Belongs to the DapA family.
 
  
 0.879
Snov_2048
D-amino-acid dehydrogenase; KEGG: mes:Meso_1843 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase.
 
   
 0.716
Snov_0156
Mandelate racemase/muconate lactonizing protein; Catalyzes the dehydration of cis-3-hydroxy-L-proline (c3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). May be involved in a degradation pathway that converts c3LHyp to L-proline, which would allow S.novella to grow on c3LHyp as a sole carbon source.
     
 0.527
Snov_0161
KEGG: atc:AGR_L_403 probable permease of ABC transporter; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component.
 
   
 0.516
Snov_0162
KEGG: pap:PSPA7_4134 ABC transporter permease; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component.
 
    0.509
Snov_0155
Proline racemase; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). May be involved in a degradation pathway that converts t3LHyp to L-proline, which would allow S.novella to grow on t3LHyp as a sole carbon source.
 
    
0.506
Snov_1660
KEGG: rpb:RPB_3648 D-amino-acid dehydrogenase; PFAM: FAD dependent oxidoreductase.
 
   
 0.505
Snov_3449
PFAM: TspO/MBR family protein; KEGG: xau:Xaut_2163 TspO and MBR like protein.
   
    0.478
Your Current Organism:
Starkeya novella
NCBI taxonomy Id: 639283
Other names: S. novella DSM 506, Starkeya novella DSM 506, Starkeya novella IAM 12100, Starkeya novella str. DSM 506, Starkeya novella strain DSM 506
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