STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Snov_0198PFAM: Malate/L-lactate dehydrogenase; KEGG: dsh:Dshi_2546 malate/L-lactate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family. (364 aa)    
Predicted Functional Partners:
Snov_0200
PFAM: amidohydrolase 2; KEGG: swi:Swit_1683 amidohydrolase 2.
       0.777
Snov_0201
PFAM: protein of unknown function DUF112 transmembrane; KEGG: ach:Achl_0355 protein of unknown function DUF112 transmembrane.
       0.775
Snov_0199
PFAM: Cupin 2 conserved barrel domain protein; KEGG: rhi:NGR_c25840 hypothetical protein.
       0.773
Snov_0202
KEGG: ddr:Deide_3p01370 hypothetical protein; putative membrane protein.
       0.744
Snov_0197
PFAM: Cupin 2 conserved barrel domain protein; KEGG: mms:mma_0820 hypothetical protein.
       0.727
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
     
 0.722
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
      
 0.688
pdhA
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
      
 0.688
Snov_0203
PFAM: conserved hypothetical protein; KEGG: mms:mma_1291 tricarboxylate binding receptor.
       0.537
Snov_0154
Malate/L-lactate dehydrogenase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using NADPH as the electron donor. Is likely involved in a degradation pathway that converts cis- and trans-3- hydroxy-L-proline (c3LHyp and t3LHyp) to L-proline, which would allow S.novella to grow on c3LHyp or t3LHyp as a sole carbon source.
  
   
0.436
Your Current Organism:
Starkeya novella
NCBI taxonomy Id: 639283
Other names: S. novella DSM 506, Starkeya novella DSM 506, Starkeya novella IAM 12100, Starkeya novella str. DSM 506, Starkeya novella strain DSM 506
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