STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Snov_0329PFAM: regulatory protein TetR; KEGG: mch:Mchl_0328 transcriptional regulator, TetR family. (220 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.761
Snov_0328
PFAM: protein of unknown function DUF924; KEGG: vap:Vapar_2217 protein of unknown function DUF924.
       0.547
Snov_2715
PFAM: protein of unknown function DUF459; KEGG: xau:Xaut_1975 hypothetical protein.
  
     0.530
Snov_3994
KEGG: nwi:Nwi_2561 hypothetical protein.
  
     0.521
Snov_1643
PFAM: RDD domain containing protein; KEGG: azc:AZC_1541 putative RDD family protein.
  
     0.517
Snov_2261
PFAM: Apolipoprotein A1/A4/E; KEGG: rpe:RPE_1474 hypothetical protein.
  
   
 0.464
Snov_3156
PFAM: Lytic transglycosylase catalytic; KEGG: oan:Oant_1733 lytic transglycosylase catalytic.
  
     0.464
Snov_0768
PFAM: plasmid stabilization system; KEGG: bam:Bamb_6594 plasmid stabilization system protein.
  
     0.454
Snov_1924
PFAM: Protein of unknown function DUF2497; KEGG: NACA, TEBP; nascent polypeptide-associated complex alpha subunit.
  
     0.449
Snov_1689
PFAM: conserved hypothetical protein; KEGG: swi:Swit_0880 hypothetical protein.
  
     0.445
Your Current Organism:
Starkeya novella
NCBI taxonomy Id: 639283
Other names: S. novella DSM 506, Starkeya novella DSM 506, Starkeya novella IAM 12100, Starkeya novella str. DSM 506, Starkeya novella strain DSM 506
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.